Pulmonary-renal syndrome refers to patients with DAH (or pathologic pulmonary purpura on physical examination implies a small-vessel, cutaneous vasculitis ( 10).. The ANCA-associated vasculitides, WG, CSS, and MPA, are grouped. . The syndrome is characterized by a triad of (1) asthma, (2) hypereosinophilia, and . Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatos...

This papers analyses the causes behind Africa’s unfortunate transformation into the source of the world’s slaves over the early modern period. We discuss the economic and technological forces leading to it, and address questions such as why were most slave buyers Europeans and most slave sellers Africans. We then relate the discussion to the long-term determinants of African underdevelopment, a...

The iron content in seminal plasma of normal (n19), oligozoospermic (n11), azoospermic (n12), oligoasthenozoospermic (n19), and asthenozoospermic (n17) subjects was estimated by using atomic absorption spectrophotometer. The concentration of iron in normal seminal plasma varied from 265 to 365 mg%. The source of iron in seminal plasma seems to be the adnexal glands and not spermatozoa, as azoos...

Growth, History, or Institutions? What Explains State Fragility in Sub-Saharan Africa We explore the determinants of state fragility in sub-Saharan Africa. Controlling for a wide range of economic, demographic, geographic and istitutional regressors, we find that institutions, and in particular the civil liberties index and the number of revolutions, are the main determinants of fragility, even...

In GN4 rat liver epithelial cells, angiotensin II (Ang II) produces intracellular calcium and protein kinase C (PKC) signals and stimulates ERK and JNK activity. JNK activation appears to be mediated by a calcium-dependent tyrosine kinase (CADTK). To define the ERK pathway, we established GN4 cells expressing an inhibitory Ras(N17). Induction of Ras(N17) blocked EGF- but not Ang II- or phorbol ...

Expression of transforming Ha-Ras L61 in NIH3T3 cells causes profound morphological alterations which include a disassembly of actin stress fibers. The Ras-induced dissolution of actin stress fibers is blocked by the specific PKC inhibitor GF109203X at concentrations which inhibit the activity of the atypical aPKC isotypes lambda and zeta, whereas lower concentrations of the inhibitor which blo...

Growth, History, or Institutions? What Explains State Fragility in Sub-Saharan Africa We explore the determinants of state fragility in sub-Saharan Africa. Controlling for a wide range of economic, demographic, geographic and istitutional regressors, we find that institutions, and in particular the civil liberties index and the number of revolutions, are the main determinants of fragility, even...

An orthogonal drawing of a graph is a planar drawing where each edge is drawn as a sequence of horizontal and vertical line segments. Finding a bend-minimized orthogonal drawing of a planar graph of maximum degree 4 is NP-hard. The problem becomes tractable for planar graphs of maximum degree 3, and the fastest known algorithm takes O(n5 logn) time. Whether a faster algorithm exists has been a ...

Introduction: Diarrheal diseases are a serious health problem and important causes of growth retardation and death in the developing world, especially those of prolonged duration. Since diarrhea is constantly found in children with zinc deficiency, very studies supported zinc supplements beneficial on the duration and severity of diarrhea among children. We review the impact of zinc effects on ...