The magnitude of intestinal parasitic infection in acquired immunodeficiency syndrome patients requires careful consideration in the developing world where poor nutrition is associated with poor hygiene and several tropical diseases. However, there have been very few studies addressing this issue in Cameroon. This study was conducted to determine the prevalence of intestinal parasitosis in HIV/...

The HIV/AIDS Regional Center in Iaşi follows approximately 1460 HIV-positive persons from 6 counties in the Moldova region of Romania. Objectives: The study aims to evaluate the number of late presenters in January 2011-November 2013. We evaluated patients admitted to the Infectious Diseases Hospital in Iaşi, for a period of 35 months, from a virological and immunological point of view. We cons...

Aim This retrospective cohort study analyzes the impact of possible risk factors on the survival chance of patients with cryptococcal meningitis. These factors include the patient's socio-economic background, age, gender, presenting symptoms, comorbidities, laboratory findings and, in particular, non-adherence versus adherence to therapy. Methods Data were collected from all adult patients admi...

Purpose of the study Since the use of more tolerable and less toxic combined antiretroviral (ARV) therapy, most drug-naïve HIV patients achieve viral suppression and immunologic recovery, combined with less AIDS related events. Nevertheless, drug switches are still frequent both as a mean of adherence and toxicity management and as a response to virologic or immunologic failure. The aim of the ...

Methods We recruited 38 antiretroviral naïve HIV-1 infected children after getting written informed consent from their parents/guardians. The study was approved by the institute ethics committee. Neutralization efficiency of the patients’ plasma was tested against tier 2 pseudoviruses (3 clade C ZM53, Du172.17 and Du156.12 and 3 clade B RHPA4259.7, TRO.11 and SC422661.8) obtained from NIH AIDS ...

The study was done to determine the anti-tuberculosis drug resistance patterns of Mycobacterium tuberculosis (MTB) in AIDS patients. Fifty antiretroviral drug naïve new AIDS patients with clinical evidence of pulmonary tuberculosis and no previous history of tuberculosis were recruited. Baseline CD4 counts and plasma viral loads (PVL) were measured by flow cytometry and RT-PCR, respectively. Sp...

BACKGROUND According to World Health Organization (WHO) guidelines, which have also been adopted by the National AIDS Control Organization (NACO), India, Efavirenz-based Anti-Retroviral Therapy (ART) is better in Human-Immunodeficiency-Virus (HIV)-infected patients who are also being treated with Rifampicin-based Anti-Tuberculous Therapy (ATT). However, Efavirenz is much more expensive. We hypo...

The progressive decline of CD4(+) T cells is a hallmark of disease progression in human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection. Whereas the acute phase of the infection is dominated by virus-mediated depletion of memory CD4(+) T cells, chronic infection is often associated with a progressive decline of total CD4(+) T cells, including the naïve subset. The...