HO (haem oxygenase) catalyses the degradation of haem to biliverdin, CO and ferrous iron via three successive oxygenation reactions, i.e. haem to alpha-hydroxyhaem, alpha-hydroxyhaem to alpha-verdohaem and alpha-verdohaem to ferric biliverdin-iron chelate. In the present study, we determined the crystal structure of ferrous alpha-verdohaem-rat HO-1 complex at 2.2 A (1 A=0.1 nm) resolution. The ...

The electronic structures of pyridine N-heterocyclic dicarbene (iPrCNC) iron complexes have been studied by a combination of spectroscopic and computational methods. The goal of these studies was to determine if this chelate engages in radical chemistry in reduced base metal compounds. The iron dinitrogen example (iPrCNC)Fe(N2)2 and the related pyridine derivative (iPrCNC)Fe(DMAP)(N2) were stud...

Chlamydiae are widespread Gram-negative pathogens of humans and animals. Salicylidene acylhydrazides, developed as inhibitors of type III secretion system (T3SS) in Yersinia spp., have an inhibitory effect on chlamydial infection. However, these inhibitors also have the capacity to chelate iron, and it is possible that their antichlamydial effects are caused by iron starvation. Therefore, we ha...

this experiment was done to evaluate the effect of nano iron oxide on some morphophysiological traits  of wheat (triticum aestivum l.) at  shahr-e qods region  in years of 2013 and 2014. experimental design, was factorial in a randomized complete block with four replications. treatments included, treatment of date of nano iron sparaying in milky  and pasty stage and another treatment was, conce...

The nutritional problems in almond orchards have increased because of alkaline soils and insufficient nutrition. This study was done to evaluate the effect of nano-chelate super plus ZFM (Zinc, Iron and Manganese) spraying on quantitative and qualitative characteristics of almond commercial cultivars. This work was carried out in factorial experiment base on randomized complete block design wit...

In acute iron poisoning, it is necessary for rational management to know whether the plasma iron exceeds the transferrin-binding capacity. A method for the rapid determination of iron in plasma is described whereby this essential information may be obtained in a few minutes. This test will help to differentiate simple iron ingestion from acute iron toxicity so the clinician may have a firmer ba...

Background: Iron overload can cause many complications and damage many organs as well as physiologic functions. Consumption of phetochemicals and flavonoids with iron chelating ability, instead of synthetic iron chelators, can be less harmful and more effective. The aim of this review is to investigate hydrophilic phytochelators in iron overload condition. Methods: In this review, the possible ...

Zero-valent iron nanoparticles (nano-Fe0) in aqueous solution rapidly inactivated Escherichia coli. A strong bactericidal effect of nano-Fe0 was found under deaerated conditions, with a linear correlation between log inactivation and nano-Fe0 dose (0.82 log inactivation/mg/L nano-Fe0 x h). The inactivation of E. coli under air saturation required much higher nano-Fe0 doses due to the corrosion ...

LTHOUGH many substances have been shown to increase iron ahsorption, the mechanism of this action is obscure. Fructose, for example, increases iron absorption in rats, and it has been suggested that its effect depends on its ability to chelate iron.4 We proposed to test this hypothesis, and to in ’estiga e possible relationships between the effects of various metabolic substrates and reducing a...

The Arabidopsis FRO2 gene encodes the low-iron-inducible ferric chelate reductase responsible for reduction of iron at the root surface. Here, we report that FRO2 and IRT1, the major transporter responsible for high-affinity iron uptake from the soil, are coordinately regulated at both the transcriptional and posttranscriptional levels. FRO2 and IRT1 are induced together following the impositio...