Cell growth and proliferative activities on titania nanotube arrays (TNA) have raised alerts on genotoxicity risk. Present toxicogenomic approach focused on epithelial HT29 cells with TNA surface. Fledgling cell-TNA interaction has triggered G0/G1 cell cycle arrests and initiates DNA damage surveillance checkpoint, which possibly indicated the cellular stress stimuli. A profound gene regulation...

All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. NPC-associated proteins containing phenylalanine-glycine repeats (FG nups) have large, flexible, unstructured proteinaceous regions, and line the NPC. A central feature of NPC-mediated transport is the binding of cargo-carrying soluble tra...

Many biological and artificial transport channels function without direct input of metabolic energy during a transport event and without structural rearrangements involving transitions from a closed to an open state. Nevertheless, such channels are able to maintain efficient and selective transport. It has been proposed that attractive interactions between the transported molecules and the chan...

the acceptance of the right project which leads to the realization of the set objectives is one of the most important issues in project-oriented companies. therefore, corporate managers prefer to work on those projects which ensures the achievement of goals such as increasing financial profits or being the top brands in their rivals market. the present  research aimed at introducing  a systemat...

the acceptance of the right project which leads to the realization of the set objectives is one of the most important issues in project-oriented companies. therefore, corporate managers prefer to work on those projects which ensures the achievement of goals such as increasing financial profits or being the top brands in their rivals market. the present  research aimed at introducing  a systemat...

the determination of gyration radius is a strong research for configuration of a macromolecule. italso reflects molecular compactness shape. in this work, to characterize the behavior of theprotein, we observe quantities such as the radius of gyration and the average energy. we studiedthe changes of these factors as a function of temperature for acetylcholine receptor protein in gasphase with n...

Tessellations of kekulenes and cycloarenes have a lot potential as nanomolecular belts for trapping transporting heavy metal ions chloride because they the best electronic properties pore sizes. The aromaticity, superaromaticity, chirality, novel electrical magnetic class known been subject several experimental theoretical studies. Through topological computations superaromatic structures with ...