Psoriasis is a chronic inflammatory skin disease. Metabolic syndrome (MS) is a combination of central obesity, dyslipidemia, glucose intolerance, and elevated blood pressure. Many epidemiological surveys have revealed the association of psoriasis with MS. Narrowband ultraviolet radiation b (NB-UVB) is an effective and widely used treatment for psoriasis. The purpose of this study was to investi...

Psoralen plus ultraviolet A (PUVA) is widely used as first-line therapy for treatment of mycosis fungoides. Narrowband ultraviolet B (NB-UVB) has also been shown to be effective for treatment of early mycosis fungoides. The aim of this retrospective study was to analyse the response to treatment and relapse-free interval for PUVA and NB-UVB therapies in mycosis fungoides. Forty patients were tr...

Narrowband ultraviolet-B (NB-UVB) phototherapy is the mainstay of vitiligo therapy. The response can be evaluated using area scoring index (VASI) and repigmentation grade. However, few studies used VASI to evaluate there are no definitive data on reduction VASI. This retrospective descriptive study aimed determine characteristics decrease in patients with after 36 48 sessions NB-UVB phototherap...

Data regarding narrowband ultraviolet B (NB-UVB) phototherapy in patients with chronic urticaria is limited. The aim of this open, controlled study was to determine whether NB-UVB is effective in treating urticaria in combination with antihistamin. A total of 81 patients with chronic urticaria were recruited, 48 of whom were randomized into the NB-UVB plus antihistamine group. The control group...

Progressive Macular Hypomelanosis is often an underdiagnosed hypo pigmented, nonscaly, macular eruption involving the trunk, abdomen, face,extremities and the buttocks with great cosmetic concern to the sufferer. Topical antifungal, corticosteroid has been ineffective in its treatment but phototherapy and topical antimicrobial has proven effective over time. Objective: This study seeks to deter...

Vascular endothelial growth factor (VEGF) promotes angiogenesis and plays important roles both in physiological and pathological conditions. VEGF receptors (VEGFRs) are high-affinity receptors for VEGF and are originally considered specific to endothelial cells. We previously reported that VEGFRs were also constitutively expressed in normal human keratinocytes and overexpressed in psoriatic epi...

We report results of a randomized, vehicle-controlled, bilateral comparison pilot study of bexarotene gel 1% with narrowband UVB (NBUVB) phototherapy for moderate to severe psoriasis. In all, 9 patients applied drug or vehicle gel to comparable target lesions up to twice daily for 10 weeks. NBUVB was initiated 2 weeks after topical therapy began. Limitations include small sample size and interi...

Phototherapy (broadband UVB, narrowband UVB (NBUVB) and heliotherapy – treatment with natural sunlight) is a commonly used treatment modality for widespread psoriasis. A similar wavelength spectrum of UVB (280-315 nm) is responsible for vitamin D synthesis in the skin. Vitamin D3, or cholecalciferol, is produced from 7-dehydrocholesterol in the basal epidermis when exposed to UVB, and is then h...

BACKGROUND The optimum treatment frequency for narrowband (TL-01) ultraviolet B (NB-UVB) in psoriasis is not yet known. We have previously found three times weekly to be preferable to five times weekly treatment in our population. OBJECTIVES To compare twice weekly with three times weekly NB-UVB phototherapy in chronic plaque psoriasis. METHODS In an observer-blinded, randomized comparison,...