An intermolecular energy transfer system is developed for studying the stability of nanoaggregate(s) (NAs) in complex solution and cell culture by one- and two-photon fluorescence microscopy and optical imaging. The system allows facile addition of one or more tumor targeting molecules, one of which is exemplified here. NAs functionalized with an MRI and optical probe, with and without folic ac...

Lysosomal phospholipase A(2) (Lpla2) is highly expressed in alveolar macrophages and may mediate the phospholipid metabolism of surfactant. Studies on the properties of this phospholipase are consistent with the presence of both phospholipase A(1) and phospholipase A(2) activities. These activities were studied through the production of O-acyl compounds, produced by the transacylase activity of...

INTRODUCTION Increasing rates of neonatal abstinence syndrome (NAS), most commonly linked to maternal opioid use, are a growing concern within clinical and public health domains. OBJECTIVES The study aims to describe the statewide burden of NAS and maternal substance use, focusing on opioids in Wisconsin from 2009 to 2014. METHODS Trends in NAS and maternal substance use diagnosis rates wer...

For a simple graph G let NG(u) be the (open) neighborhood of vertex u ∈ V (G). Then G is neighborhood anti-Sperner (NAS) if for every u there is a v ∈ V (G)\{u} with NG(u) ⊆ NG(v). And a graph H is neighborhood distinct (ND) if every neighborhood is distinct, i.e., if NH(u) 6= NH(v) when u 6= v, for all u and v ∈ V (H). In Porter and Yucas [3] a characterization of regular NAS graphs was given:...

Single-unit recordings of nucleus accumbens septi (NAS) neurons in halothane-anesthetized rats revealed that microinfusions of morphine into the ventral tegmental area (VTA) primarily inhibited spontaneously active NAS units. These inhibitory effects were reversed by alpha-flupenthixol (s.c.), suggesting a role for dopamine (DA) in the observed opiate-induced effect. VTA opiate microinfusions a...

Accounting research has extensively debated the impact of non-audit services (NAS) provided by auditors on auditor independence and on clients’ financial reporting quality. Most research on this debate uses data resulting from a SEC disclosure rule in 2000. We provide evidence on this controversy using data from the years 1978-1980 to re-examine the relation between fees for NAS provided by aud...

Neonatal abstinence syndrome (NAS) is the term used to describe the presence of withdrawal symptoms in neonates exposed prenatally to opiates. Much of what is known about NAS is based on the biomedical model of illness. There is less consideration of the social, historical, and political influences on knowledge development about the NAS phenomenon. Social construction presents an alternate fram...

We tested the power of tumor necrosis factor (TNF)-alpha and/or leptin in predicting the degree of liver involvement in children with nonalcoholic fatty liver disease (NAFLD). We measured serum levels of TNF-alpha and leptin and computed NAFLD activity score (NAS) (NAS >or= 5, diagnostic of nonalcoholic steatohepatitis [NASH]) in 72 consecutive biopsy-proven NAFLD cases (training and validation...

This paper proposes a CIFS Server virtualization method which requires no proprietary software or hardware for clients or NAS units. The method is implemented as an in-band network application between clients and NAS units, and it provides users and administrators with a single virtual NAS system that incorporates all their units. Since almost all name resolution operations are performed by ind...

This qualitative study identifies and describes different ways in which newly graduated nurse anesthetists (NAs) experience and perceive nurse anesthesia. It explains different approaches to nurse anesthesia care and, thus, to clinical nursing care (in an anesthesia and surgical context), provided by new NAs. One month after graduation, all NAs who had completed an anesthesia nursing program re...