background: despite the prevalence of non-alcoholic fatty liver disease (nafld) and non-alcoholic steatohepatitis (nash), no treatment has been proven to be effective in these common diseases. although many studies have shown that lifestyle modifications such as increasing physical activities and exercise could be effective in the treatment of these common diseases, the optimal strategy is stil...

the strategic pricing decisions of assembly products in assembly products supply chain are studied in this paper. firstly, a two-stage assembly products supply chain model is developed. by building nash game model, the nash equilibrium solution of pricing strategy of supplier and assemblers is obtained. next, a union decision model is built to analyze the optimal combination pricing strategy of...

BACKGROUND Patients with biopsy-proven NASH and especially those with fibrosis are at risk for progressive liver disease, emphasizing the clinical importance of developing non-invasive biomarkers for NASH and NASH-related fibrosis. AIM This study examines the performance of a new biomarker panel for NASH and NASH-related fibrosis with a combination of clinical and laboratory variables. METH...

Oxidative stress is one of the key mechanisms responsible for liver damage and disease progression in non-alcoholic steatohepatitis (NASH). Antioxidants try to combat the oxidative stress and minimise the oxidative stress. In this study, the comparative effect of pioglitazone, quercetin and hydroxy citric acid on lipid peroxidation and antioxidants in experimentally induced NASH has been studie...

Nonalcoholic steatohepatitis (NASH) has become a global chronic liver disease, but no effective medicine has been proven to cure it. This study investigated the protective effects of genistein, a phytoestrogen, on NASH and examined whether it has any effect on hepatic PPARγ. Male Sprague-Dawley rats were divided into four groups: control group fed ad libitum with standard rat diet, NASH group f...

For each non-negative integer n, we define the n-th Nash blowup of an algebraic variety, and call them all higher Nash blowups. When n = 1, it coincides with the classical Nash blowup. We prove that sufficiently high Nash blowups separate analytic branches. We also determine for a monomial curve in characteristic zero when its higher Nash blowups are smooth.

This paper studies the Nash stability in hedonic coalition formation games. We address the following issue: for a general problem formulation, is there any utility allocation method ensuring a Nash-stable partition? We propose the definition of the Nash-stable core and we analyze the conditions for having a non-empty Nash-stable core. More precisely, we prove that using relaxed efficiency in ut...

With the increasing use of different types of auctions in market designing, modeling of participants’ behaviors to evaluate the market structure is one of the main discussions in the studies related to the deregulated power industries. In this article, we apply an approach of the optimal bidding behavior to the Iran wholesale electricity market as a restructured electric power industry and mode...

One of the main questions regarding nonalcoholic fatty liver disease is the molecular background of the transition from simple steatosis (SS) to the inflammatory and fibrogenic condition of steatohepatitis (NASH). We examined the gene expression changes during progression from histologically normal liver to SS and NASH in models of obesity caused by hyperphagia or a high-fat diet. Microarray-ba...