Methotrexate is a folic acid antagonist and immunosuppressive agent, which is being increasingly used in various ocular inammatory diseases. Its use in ophthalmology has been increasing in recent years because of its anti-inammatory activity and corticosteroid-sparing objective. It is currently used in recurrent anterior uveitis, intermediate uveitis, posterior or panuveitis, scleritis, perip...

Background. Necrotizing sialometaplasia (NS) is an uncommon benign reactive necrotizing inflammatory process involving minor salivary gland that often mimics malignancy both clinically and histopathologically. Case Report. We report the case of a healthy 26-year-old man with a painless swelling in the hard palate near the middle raphe, asymptomatic, well limited, and raised edges. The patient w...

Acute Necrotizing Ulcerative Gingitivitis (ANUG) is a distinct and specific disease. This disease entity has been described as far back as the days of Hippocrates and is known by many synonyms. With the advent of antibiotics and with improved nutritional status, the incidence has decreased and even become extinct in developed countries. However, with the increasing incidence of severe immunodef...

A trial was performed to evaluate the efficacy of diquat (6,7-dihydrodipyrido[1,2-a:2',1'-c]pyrazinediium dibromide) against an acute experimental infection of Flavobacterium columnare in channel catfish, Ictalurus punctatus. Diquat is an Environmental Protection Agency-approved herbicide and has the potential to be legally and practically used against columnaris. Channel catfish were challenge...

BACKGROUND Psoriasis is a common, nonulcerative skin disorder. OBSERVATIONS We describe 3 men recently referred to our institution for evaluation and treatment of severe, ulcerative psoriasis that ultimately was determined to be aggressive, cytotoxic, cutaneous lymphoma. Each had a history of relatively indolent, nonulcerative patches and plaques (duration, 2-45 years) that changed to ulcerat...

A case of poor-doing cattle in a feedlot in the prairie region of western Canada was investigated. Clinical examination revealed mild to severe chronic ulcerative stomatitis. Histopathological examination confirmed plant material embedded within the lesions. Yellow foxtail (Setaria lutescens) was grossly visible in clover silage fed to the cattle. This case highlights the need to consider plant...

<b>Purpose:</b> of review: To discuss peripheral ulcerative keratitis, with a focus on the evaluation and management associated systemic diseases. <b>Recent findings:</b> Peripheral keratitis (PUK) is sight-threatening condition that often defined by presence crescent-shaped area corneal thinning, an epithelial defect, inflammatory infiltrate. It highly rheumatoid arthri...

Necrotizing Sialometaplasia (NS) is a benign, self-limiting inflammatory disease of the mucus-secreting glands, and this illness mainly involves the minor salivary glands. The significance of NS resides in its clinical and histopathological resemblance to malignancy. We present here a case of necrotizing sialometaplasia on the soft palate, and this was accompanied by adenoid cystic carcinoma. W...

INTRODUCTION Scleritis and peripheral ulcerative keratitis are ocular manifestations found in many inflammations and infections. Therefore, their association should prompt a search for inflammatory or infectious causes that may be life-threatening, especially in the context of AIDS due to HIV infection. FINDINGS We report the case of a 37-year-old female, first seen in 2011 with a nodular scl...