Identifying the pathogen responsible for culture-negative valve endocarditis often depends on molecular studies performed on surgical specimens. A patient with Ehlers-Danlos syndrome who had an aortic graft, a mechanical aortic valve, and a mitral anulloplasty ring presented with culture-negative prosthetic valve endocarditis and aortic graft infection. Research-based polymerase chain reaction ...

background: lower respiratory tract infections (ltris) are among the most common infectious diseases with potential life-threatening complications. methods: the study consisted of 426 patients with suspected ltris from mid and far western region of nepal between september 2011 and july 2014. the specimens were collected and processed according to the standard microbiological methods at the cent...

the genus teucrium (germander) belongs to the family lamiaceae, within the subfamily ajugoideae .teucrium polium l. (labiatae) has long been recognized in folk medicine in the treatment of many pathophysiological implications, such as gastrointestinal disorders, inflammations, diabetes and rheumatism. in this study antimicrobial activity of two crude extracts obtained from teucrium polium l. wa...

colletotrichum species are associated with citrus plants as pathogens, saprobes and endophytes. according to the most recent multigene phylogenetic analysis, a lot of changes were happened in the taxonomy and species delimitation in the genus colletotrichum. in this investigation, 292 colletotrichum isolates were obtained from leaves, fruits and stems of citrus species at golestan, mazandaran, ...

OBJECTIVES To search for imaging characteristics distinguishing patients with successful from those with futile microbiological pathogen detection by CT-guided biopsy in suspected spondylodiscitis. METHODS 34 consecutive patients with suspected spondylodiscitis underwent CT-guided biopsy for pathogen detection. MR-images were assessed for inflammatory infiltration of disks, adjacent vertebrae...

The Arabidopsis (Arabidopsis thaliana) WRKY7 gene is induced by pathogen infection and salicylic acid (SA) treatment and may therefore play a role in plant defense responses. Here, we show that WRKY7 is localized in the nucleus, recognizes DNA molecules with the W-box (TTGAC) elements, and functions as a transcriptional repressor in plant cells. To study its biological functions directly, we ha...

Previous studies have suggested that procalcitonin is a reliable marker for predicting bacteremia. However, these studies have had relatively small sample sizes or focused on a single clinical entity. The primary endpoint of this study was to investigate the diagnostic accuracy of procalcitonin for predicting or excluding clinically relevant pathogen categories in patients with suspected bloods...

Serum antibodies from patients with Lyme disease (LD) were used to affinity select peptide epitopes from 12 large random peptide libraries in phage display format. The selected peptides were surveyed for reactivity with a panel of positive sera (from LD patients) and negative sera (from subjects without LD), thus identifying 17 peptides with a diagnostically useful binding pattern: reactivity w...

Methods This prospective randomized controlled study was carried out on 60 mechanically ventilated patients with gram negative VAP. Inclusion criteria: Adult mechanically ventilated patients diagnosed to have Gram negative VAP confirmed:· Radiologically (new chest xray infiltrate). · Microbiologically (positive culture from aspirate of endotracheal tube (ETT). · Clinically (fever, leukocytosis ...

Campylobacter concisus, a member of the human’s oral microflora, is Gram-negative, fastidious, microaerophilic bacterium. However, it debatable whether should be recognised as commensal human cavity, or an opportunistic pathogen has been linked to and gastrointestinal infections. But there no doubt that its biofilm-forming capacity enhanced survival mechanism pathogen. Hence, through our invest...