نتایج جستجو برای: negative sequence current nsc

تعداد نتایج: 1635815  

Journal: :Molecular and cellular biology 2006
Xiaohua Su Vidya Gopalakrishnan Duncan Stearns Kenneth Aldape Fredrick F Lang Gregory Fuller Evan Snyder Charles G Eberhart Sadhan Majumder

Medulloblastoma, one of the most malignant brain tumors in children, is thought to arise from undifferentiated neural stem/progenitor cells (NSCs) present in the external granule layer of the cerebellum. However, the mechanism of tumorigenesis remains unknown for the majority of medulloblastomas. In this study, we found that many human medulloblastomas express significantly elevated levels of b...

2015
Or Sperling J. Mason Earles Francesca Secchi Jessie Godfrey Maciej A. Zwieniecki Lucas C.R. Silva

Cellular respiration depletes stored carbohydrates during extended periods of limited photosynthesis, e.g. winter dormancy or drought. As respiration rate is largely a function of temperature, the thermal conditions during such periods may affect non-structural carbohydrate (NSC) availability and, ultimately, recovery. Here, we surveyed stem responses to temperature changes in 15 woody species....

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Andrew T Timberlake Charuta G Furey Jungmin Choi Carol Nelson-Williams Erin Loring Amy Galm Kristopher T Kahle Derek M Steinbacher Dawid Larysz John A Persing Richard P Lifton

Non-syndromic craniosynostosis (NSC) is a frequent congenital malformation in which one or more cranial sutures fuse prematurely. Mutations causing rare syndromic craniosynostoses in humans and engineered mouse models commonly increase signaling of the Wnt, bone morphogenetic protein (BMP), or Ras/ERK pathways, converging on shared nuclear targets that promote bone formation. In contrast, the g...

2006
William P. Tong Kurt W. Kohn David B. Ludlum

The modification of DMA by the haloethylnitrosoureas is probably responsible for their antitumor activity. A current hypothesis relates this cytotoxic action to the transfer of haloethyl groups from the nitrosourea to DNA followed by a second reaction of the haloethyl group with the opposite DNA strand. However, other modifications besides interstrand cross-links are introduced into DNA, raisin...

Journal: :Nucleic acids research 1975
D E Garfin H W Boyer H M Goodman

Substrate recognition by the EcoRI restriction endonuclease was investigated by analysis of the nucleotide sequences at the sites of enzymatic cleavage in various DNA molecules. 5'-end labeling and homochromatographic fingerprinting led to the determination of a 17-base-pair sequence spanning the EcoRI site of simian virus 40 DNA and a 15-base-pair sequence overlapping the EcoRI site of Col El ...

1996
Srinivas Katkoori Ranga Vemuri

We present an architectural power simulation technique for PLA-based controllers. The contributions of this work are (1) a simple but eecient power characterization of PLAs; and (2) a strategy for developing a simulatable power model from the input description. Node Switching Capacitance (nsc) of a sub-component (such as and plane) in a PLA is the average capacitance switched by a node in the s...

Journal: :Functional Ecology 2021

Abstract Tropical tree species span a range of life‐history strategies within fast–slow continuum. The position this continuum is thought to reflect negative relationship between growth and storage, with fast‐growing allocating more carbon slow‐growing investing in storage. For tropical species, the storage has been largely studied on seedlings less so adult trees. We evaluated how stored non‐s...

2016
Yan-Chuang Han Yoon Lim Michael D. Duffieldl Hua Li Jia Liu Nimshitha Pavathuparambil Abdul Manaph Miao Yang Damien J. Keating Xin-Fu Zhou

Although it is possible to generate neural stem cells (NSC) from somatic cells by reprogramming technologies with transcription factors, clinical utilization of patient-specific NSC for the treatment of human diseases remains elusive. The risk hurdles are associated with viral transduction vectors induced mutagenesis, tumor formation from undifferentiated stem cells, and transcription factors-i...

Journal: :South African Journal of Higher Education 2016

Journal: :The New phytologist 2008
Sara Palacio Rubén Milla Jorge Albuixech Carmen Pérez-Rontomé Jesús Julio Camarero Melchor Maestro Gabriel Montserrat-Martí

This study assesses how different phases of shoot growth underlie seasonal change in leaf and stem dry matter content (LDMC and SDMC, respectively) of 12 woody Mediterranean species. The relationship between LDMC and nonstructural carbohydrate (NSC) concentrations is also explored and the seasonal vs interspecies variability of LDMC compared. LDMC, SDMC and shoot elongation rate (SER) were meas...

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