نتایج جستجو برای: neoadjuvant hemotherapy

تعداد نتایج: 15195  

2016
Sarah M. Schwarzenböck Anna Knieling Michael Souvatzoglou Jens Kurth Katja Steiger Matthias Eiber Irene Esposito Margitta Retz Hubert Kübler Jürgen E. Gschwend Markus Schwaiger Bernd J. Krause Mark Thalgott

PURPOSE Recent studies have shown promising results of neoadjuvant therapy in prostate cancer (PC). The aim of this study was to evaluate the potential of [11C]Choline PET/CT in therapy response monitoring after combined neoadjuvant docetaxel chemotherapy and complete androgen blockade in locally advanced and high risk PC patients. RESULTS In [11C]Choline PET/CT there was a significant decrea...

Journal: :Clinical advances in hematology & oncology : H&O 2015
Patricia Cortazar Paul G Kluetz

Neoadjuvant treatment of breast cancer initially was limited to patients with locally advanced breast cancer in which downstaging was necessary. Now, neoadjuvant trials have become an increasingly common way to facilitate the rapid assessment of new cancer therapies. The appeal of neoadjuvant trials is that they provide the opportunity to study translational science, tumor biomarkers, and inter...

2011
Zhien Feng Wei Guo Chenping Zhang Qin Xu Ping Zhang Jian Sun Hanguang Zhu Zhonghe Wang Jiang Li Lizhen Wang Bingshun Wang Guoxin Ren Tong Ji Wenyong Tu Xihu Yang Weiliu Qiu Li Mao Zhiyuan Zhang Wantao Chen

BACKGROUND Cyclin D1 (CCND1) has been associated with chemotherapy resistance and poor prognosis. In this study, we tested the hypothesis that CCND1 expression determines response and clinical outcomes in locally advanced head and neck squamous cell carcinoma (HNSCC) patients treated with neoadjuvant chemotherapy followed by surgery and radiotherapy. METHODOLOGY AND FINDINGS 224 patients with...

2013
Qianxin Jia Junqing Xu Weifeng Jiang Minwen Zheng Mengqi Wei Jianghao Chen Ling Wang Yi Huan

BACKGROUND Anti-angiogenesis is a promising therapeutic strategy for locally advanced breast cancer. We performed this phase II trial to evaluate the anti-angiogenesis and anti-tumor effect of rh-endostatin combined with docetaxel and epirubicin in patients with locally advanced breast cancer by dynamic contrast-enhanced magnetic resonance imaging in 70 previously untreated locally advanced bre...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Hua Yuan Jiuan Chen Yiqiang Liu Tao Ouyang Jinfeng Li Tianfeng Wang Zhaoqing Fan Tie Fan Benyao Lin Yuntao Xie

PURPOSE The association between PIK3CA mutations and response to neoadjuvant chemotherapy in women with primary breast cancer is not fully elucidated. EXPERIMENTAL DESIGN PIK3CA mutations in breast cancer tissues that were taken prior to the initiation of neoadjuvant chemotherapy were identified in 729 operable primary breast cancer patients who received neoadjuvant chemotherapy. Among these,...

Journal: :Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2006
Günter Singbartl Wolf Schleinzer

This symposium (Nottwil/Lucerne, Switzerland, January 20./21. 2006,) gives you the latest review / clinical results / experimental data on autologous transfusion: Routine leucodepletion of preoperative autologous deposit, immunological perspectives, special processing of bacterially contaminated autologous blood, pro and con concerning autologous blood supply as a reasonable alternative, autolo...

Journal: :Interactive cardiovascular and thoracic surgery 2012
Reza Bagheri Mohammad Taghi RajabiMashhadi Kiyarash Ghazvini Amir Asnaashari Ali Zahediyan Mehdi Abasi Sahebi

Respiratory complication is one of the important postoperative complications of oesophageal cancer. The aim of this study was to evaluate whether neoadjuvant chemotherapy before surgery is effective for postoperative respiratory complications. In this study, patients with oesophageal cancer were divided into two group: one with neoadjuvant therapy and the other without neoadjuvant therapy. Befo...

Journal: :iranian journal of radiology 0
saeed naghibi islamic azad university

methods study on 34 patients diagnosed with rectal adenocarcinoma referred to oncology clinic was conducted. the treatment plan included 4050 cgy radiotherapy and 5fu, xeloda chemotherapy. all patients were assessed with 1/5 t mri 6 to 8 weeks after treatment. t1 and t2 images with sagittal, cronal and axial planes with and without contrast agent were obtained and interpreted by two radiologist...

Journal: :archives of breast cancer 0
borna farazmand radiation oncology research center (rorc), department of radiation oncology, cancer institute, tehran university of medical sciences, tehran, iran maisa yamrali radiation oncology research center (rorc), department of radiation oncology, cancer institute, tehran university of medical sciences, tehran, iran reza ghalehtaki radiation oncology research center (rorc), department of radiation oncology, cancer institute, tehran university of medical sciences, tehran, iran mehran habibi department of surgery, johns hopkins bayview campus, baltimore, usa

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