The present experiment was designed t investigate the role of posterior neocortex (areas 17, 18 and 18a) in the maintenance of performance on the radial maze. Following training to criterion on the 8-arm radial maze, rats received either sham operations, bilateral eye enucleations, lesions of posterior neocortex, or combined enucleations and lesions of posterior neocortex. While the enucleated ...

Linking synaptic connectivity to dynamics is key to understanding information processing in neocortex. Circuit dynamics emerge from complex interactions of interconnected neurons, necessitating that links between connectivity and dynamics be evaluated at the network level. Here we map propagating activity in large neuronal ensembles from mouse neocortex and compare it to a recurrent network mod...

The neural circuits of the mammalian neocortex are crucial for perception, complex thought, cognition, and consciousness. This circuitry is assembled from many different neuronal subtypes with divergent properties and functions. Here, we review recent studies that have begun to clarify the mechanisms of cell-type specification in the neocortex, focusing on the lineage relationships between neoc...

The olfactory cortex is part of the mammalian cerebral cortex together with the neocortex and the hippocampus. It receives direct input from the olfactory bulbs and participates in odor discrimination, association, and learning (Bekkers and Suzuki, 2013). It is thought to be an evolutionarily conserved paleocortex, which shares common characteristics with the three-layered general cortex of rep...

Existing information technology tools are harnessed and integrated to provide digital specification of human consciousness of individual persons. An incremental compilation technology is proposed as a transformation of LifeLog derived persona specifications into a Canonical representation of the neocortex architecture of the human brain. The primary purpose is to gain an understanding of the se...

The size and surface area of the mammalian brain are thought to be critical determinants of intellectual ability. Recent studies show that development of the gyrated human neocortex involves a lineage of neural stem and transit-amplifying cells that forms the outer subventricular zone (OSVZ), a proliferative region outside the ventricular epithelium. We discuss how proliferation of cells within...