OBJECTIVE Air leak syndromes including pneumothorax, pneumomediastinum and pulmonary interstitial emphysema are frequent in neonatal period. Mechanical ventilation with positive pressure is one of the most common causes of these syndromes. The aim of this study was to evaluate predisposing factors and incidence of pneumothorax in newborns under mechanical ventilation. METHODS This descriptive...

Traditional management of neonatal respiratory failure has been accomplished with mechanical ventilation delivered by time-cycled, pressure-limited techniques. Although easy to use, this modality results in the delivery of tidal volumes that vary according to pulmonary compliance. In contrast, volume-targeted ventilation delivers a selected tidal volume at variable peak inspiratory pressure, re...

Spontaneous pneumothorax is a recognised cause of respiratory distress in the neonatal period. Spontaneous pneumothorax occurring during the neonatal period in a term neonate is rare. We report a case of symptomatic spontaneous pneumothorax associated with congenital heart disease which needed intercostal drainage and mechanical ventilation in our NICU unit.

Background: Neonatal respiratory distress syndrome (NRDS), a life-threatening pulmonary disorder, involves 1% of all deliveries worldwide. Shallow breathing causes restlessness in infants, which itself affects pulmonary function; thus, sedative medications are used to preserve better pulmonary function. There are different opinions about the benefits and superiority of these dr...

With favourable and extensive experience in the neonatal intensive care unit (ICU) and the recent positive experience in the adult ICU, high-frequency ventilation has become a valuable alternative to conventional ventilation in acute lung injury. To arrive at this point, physicians' understanding of the characteristics and kinetics of acute lung injury had to become more distinct, and it was ne...

OBJECTIVE To estimate the efficacy of a rescue course of antenatal corticosteroids in twin pregnancies. DESIGN Retrospective cohort study. SETTING Tertiary-care centre. POPULATION Twins born from 24 to <34 weeks of gestation in a single maternal and fetal medicine practice from 2006 to 2011. METHODS We compared neonatal outcomes in 88 twins exposed to a single course of corticosteroids ...

background : mechanical ventilation is used for some infants in neonatal intensive care units (nicu) due to many physiological and clinical causes. since these patients have endotracheal tubes, cleaning and keeping the airways open through suctioning should be done to increase oxygenation. this study aimed to evaluate effect of open and closed suctioning methods on respiratory parameters of inf...

background: endotracheal or tracheostomy tube in mechanically ventilated patients disturb verbal communication with others. therefore, patients are frustrated of requesting for their needs or problems related to artificial breathing. therefore investigating self-experiences of these patients can be applied in providing them with a better care by clinical personnel. methods: this is a qualitativ...

Respiratory distress syndrome (RDS) is the leading cause of neonatal respiratory distress in our country and is the commonest disorder requiring assisted ventilation all over the world(l,2), Exogenous surfactant administration is now an established mode of therapy in neonatal RDS (hyaline membrane disease, HMD). Ever since the first report of successful surfactant replacement therapy in neonate...