In spina bifida, the neural tube fails to close during the embryonic period. Exposure of the neural tube to the amniotic fluid during pregnancy causes additional neural damage. Intrauterine tissue engineering using a biomaterial seeded with stem cells might prevent this additional damage. For this purpose, autologous cells from the amniotic fluid are an attractive source. To close the defect, i...

A newborn with anencephaly does not have parts of the brain or skull. It is a significant birth condition. particular sort Neural Tube Defect (NTD) present. The neural tube helps form baby’s and skull (upper segment tube), spinal cord, back bones (lower half as it grows closes.When top portion completely seal, occurs. As consequence, many babies are born without cerebrum, which part responsible...

THE aetiology of anencephaly and/or spina bifida (neural tube defects) is still obscure. Most investigators are now agreed on a multifactorial causation with an important genetic factor and a substantial environmental component. The genetic factor is probably polygenic, but the mechanism by which it acts remains unknown. Recently, drugs that stimulate ovulation, particularly clomiphene, have be...

The growth of prenatal diagnosis and selective abortion has provided profound relief for many couples, but it has also aroused opposition on moral grounds and has been criticised as overshadowing other approaches to the reduction of perinatal deaths and handicapping disorders of childhood. Fundamental research into the causes and true prevention of birth defects, especially neural defect, could...