Esophageal cancer incidence rates have been increasing over the past years and survival remain low. According to Global Cancer Observatory, 3.1% of new cases consists esophageal 5.5% deaths was due cancer. Histologic classification comprises either squamous cell carcinoma (SCC) or Adenocarcinoma. Other types are reported be uncommon. We present a case 33-year old male admitted progressive dysph...

Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. This updated classification was developed with the aim to adhere to the principles of reproducibility, clinical significance, and simplicity in order to minimize the number of unclassifiable lesions. Major changes in the revised classificat...

Abstract Esophageal basaloid squamous cell carcinoma may resemble small biopsy specimens and cause difficulties in pathology diagnosis. We aimed to explore the pathological features of carcinomas that mimic clarify their diagnostic prognostic features. This study will contribute draw attention an important pitfall diagnosis endoscopic esophagus. Thirty esophageal were reviewed compared with 13 ...

Neuroendocrine tumor of the lung is classified into four subtypes according to the recent World Health Organization Classification: typical carcinoid, atypical carcinoid, small cell carcinoma, and large cell neuroendocrine carcinoma (LCNEC) [1]. LCNEC is a relatively rare histopathological subtype of lung carcinoma, which accounts for approximately 3% of all lung carcinomas [1]. It has been wel...

neuroendocrine cells. Neuroendocrine cells are distributed throughout the gastrointestinal tract, pancreas, lung, thyroid, adrenal gland, and many other organs (1). The gastrointestinal tract has the largest population of neuroendocrine cells, but neuroendocrine malignancies are rare in the colon or rectum (2), accounting for less than 1 percent of all colorectal cancer (3). A PubMed search rev...

OBJECTIVE The aim of this study was to analyze trends in a variety of prognostic factors for neuroendocrine lung carcinomas through analysis of 2 groups of surgically treated patients. PATIENTS AND METHODS Group A contained the first 361 patients, treated between 1980 and 1997. That group was analyzed retrospectively and contained 261 patients with typical carcinoid tumors, 43 with atypical c...

Mixed adenoneuroendocrine carcinoma (MANEC) is a rare disease, which mostly occurs in the gastrointestinal tract and pancreas. Here we report a case of gastric MANEC with tri-lineage differentiation in which only the neuroendocrine component had metastasized to the liver. Liver and gastric masses were detected by abdominal computed tomography, and the preoperative relationship between liver and...

BACKGROUND Prostatic neuroendocrine carcinomas comprise <1% of all prostate neoplasms, and approximately 200 cases have been reported in the literature. We undertook this study to describe the experience in the management of prostatic neuroendocrine carcinoma with androgen-deprivation therapy (ADT). METHODS We designed a retrospective, descriptive and observational study. In patients with sus...

Small-cell neuroendocrine carcinoma is a high-grade carcinoma rarely encountered in extra-pulmonary sites. A 40-year-old lady presented with epigastric pain and was noted to have an ulcerated small-cell neuroendocrine carcinoma in her duodenum with liver metastases. She underwent palliative chemotherapy but unfortunately passed away. Duodenal SCNC is an unusual malignancy with an aggressive phe...

We report a unique case of synchronous double primary gastric cancer consisting of adenocarcinoma components with micropapillary features and composite glandular-endocrine cell carcinoma components. The patient was a 53-year-old man presenting with a 6-month history of epigastric pain and diarrhea. A subtotal gastrectomy was performed. Histologically, one tumor was composed of micropapillary ca...