Background and Aim: Endovascular neurosurgery is widely accepted as a useful modality for the management of neurovascular disorders. This retrospective study aimed to evaluate the causes of diagnostic and therapeutic neuroendovascular procedures, as well as the prevalence, type, location and management of vascular pathologies observed in Firoozgar Hospital, Tehran City, Iran. Methods and Mater...

Large intraluminal cervical carotid artery filling defects consistent with mural thrombi were angiographically demonstrated during acute hemispheric neurologic episodes. These thrombi disappeared benignly as shown by serial angiography in 2 patients treated with intravenous heparin and spontaneously in 1 patient treated surgically. Thus, partially obstructing cervical carotid artery thrombi may...

Hyperekplexia is a rare, nonepileptic, genetic, or sporadic neurologic disorder characterized by startle responses to acoustic, optic, or tactile stimuli. Genetic defects in glycine receptors as well as encephalitis, tumors, inflammation, and disgenesis are among the etiologic causes of the disease. The main problem in hyperekplexia is the incomplete development of inhibitory mechanisms or exag...

During pregnancy, smoking involves a higher risk both for women and their unborn children to suffer serious diseases such as placental cord changes, placenta previa, ectopic pregnancy, intrauterine growth retardation, pre-eclampsia, spontaneous abortion, premature birth, low birth weight, birth defects, congenital urinary tract anomalies, fetal and infant deaths, sudden infant death syndrome, l...

Binasal hemianopia is a rarely encountered visual field defect. We examined two asymptomatic female patients, aged 17 and 83, with complete binasal hemianopia. Both patients had unremarkable eye exams except for the visual field deficits and minimally reduced visual acuity and color vision. Both patients had normal neuroimaging. These are the first reported cases of complete binasal visual fiel...

Urea cycle defects (UCDs) typically present with hyperammonemia, the duration and peak levels of which are directly related to the neurologic outcome. Liver transplantation can cure the underlying defect for some conditions, but the preexisting neurologic status is a major factor in the final outcome. Multicenter data indicate that most of the children who receive transplants remain significant...

BACKGROUND Hereditary Coproporphyria (HCP) is characterized by abdominal pain, neurologic symptoms and psychiatric disorders, even if it might remain asymptomatic. The pathophysiology of both neurologic and psychiatric symptoms is not fully understood. Therefore, aiming to evaluate a possible role of brain blood flow disorders, we have retrospectively investigated cerebral perfusion patterns in...

Background: About 40 thousand newborns are delivered annually with fetal alcohol syndrome (FAS). It induces serious CNS complications. Methods: In a review of, the word “fetal alcohol syndrome” was searched in PubMed and Google Scholar and the retrieved articles were summarized. Results: Many studies showed that alcohol can cause more defects in fetus than heroin, cocaine and marijuana. The pos...

LLOWING the introduction of liver therapy for pernicious anemia in I9L6’ the curability of the neurologic manifestations of this disease became a matter of intense interest and large series of patients with acute, chronic and residual neurologic defects were treated with lightly cooked liver and oral liver extracts. It was found that while this treatment restored satisfactory blood levels and r...

The author reviews the clinical and pathological features of sacral agenesis, with emphasis on the resulting neurologic deficits and the association in many cases with maternal diabetes mellitus. The demonstrated wide spectrum genetic defects are reviewed in the context of molecular genetic regulation of ontogenesis of bony and neural spinal structures. Differential diagnosis from meningomyeloc...