purpose : to report an atypical case of acanthamoeba keratitis. patients & methods : a 19-year-old girl presented with a history of recurrent herpetic keratitis and a history of short-time contact lens wear. laboratory work-up for herpetic, bacterial, and acanthamoeba sources were negative and the patient failied to follow up. on later presentation she had corneal necrotizing stromal ulcer need...

BACKGROUND This study was done to evaluate the visual and anatomical outcomes of topical regenerating agents as a novel therapy for neutrophic corneal ulcer (NCU) secondary to acanthamoeba infection. FINDINGS A 20-year-old woman with a history of contact lens wear was referred to our hospital for keratitis after responding poorly to conventional treatment. In vivo confocal microscopy images s...

The purpose of the study was to evaluate the efficacy of multilayer amniotic transplantation (AMT) for reconstruction of corneal stroma and epithelium. Corneal ulcer (28) was a consequence of a previous infectious or neurotrophic keratitis. In the first group (17) ulcer was covered with monolayer AM, while in the other group (11) there were two or more layers of AM situated in the ulcer and the...

The past decade has witnessed the revival of amniotic membrane transplantation (AMT) in ophthalmology. The importance of amniotic membrane lies in its ability to reduce inflammation and scarring, enhance epithelialization and wound healing, and in its antimicrobial properties. Amniotic membrane has recently been used as a substrate for culturing limbal stem cells for transplantation. It has als...

TOPIC The clinical features and management strategies for varicella-zoster virus (VZV) infections of the cornea, lids, and adnexa. CLINICAL RELEVANCE Herpes zoster ophthalmicus (HZO) can result in a myriad of chronic and recurrent complications that may be sight threatening. Surgical intervention is the mainstay of treatment, and advancements in this area may lessen the complications of HZO i...

PURPOSE To determine risk factors and clinical signs that may differentiate between bacterial, fungal, and acanthamoeba keratitis among patients presenting with presumed infectious keratitis. DESIGN Hospital-based cross-sectional study. METHODS We examined the medical records of 115 patients with laboratory-proven bacterial keratitis, 115 patients with laboratory-proven fungal keratitis, an...