In this study, a comparison of the effects of neutron and electron irradiation of aqueous DNA solutions was investigated to characterize potential neutron signatures in DNA damage induction. Ionizing radiation generates numerous lesions in DNA, including base and sugar lesions, lesions involving base-sugar combinations (e.g. 8,5'-cyclopurine-2'-deoxynucleosides) and DNA-protein cross-links, as ...

Introduction: In recent years, the use of neutrons has increased in various fields such as medicine and industry. One of the important applications of neutrons is in medical research. Neutrons have greater linear energy transfer than gamma rays and are considered more dangerous radiation. Hence, the detection and determination of neutron dose is a very important and vital issu...

AIMS AND BACKGROUND Neutron rays produce high linear energy transfer radiation, which has particular radiobiological characteristics. The aim of the study was to observe the curative effects and complications of external irradiation combined with californium-252 (252Cf) neutron intraluminal brachytherapy for treatment of cervical carcinoma. METHODS AND STUDY DESIGN From December 2000 to Decem...

The University of Missouri Research Reactor has designed and constructed a thermal neutron beam line for use in small animal boron neutron capture therapy (BNCT) experiments. Details of the facility have been previously reported by Brockman et al.[1] and Pozzi et al.[2]. The facility utilizes a 15.24 cm diameter beam tube that extends from the beryllium reflector to the biological shield, a dis...

SmFeAsO1−xFx was irradiated in a fission reactor by a fast (E > 0.1 MeV) neutron fluence of 4 × 1021 m−2. The introduced defects increased the normal state resistivity due to a reduction in the mean free path of the charge carriers. This leads to an enhancement of the upper critical field at low temperatures. The critical current density within the grains, Jc, increases upon irradiation. The se...

Boron neutron capture therapy (BNCT) is a form of radiation therapy that requires selective uptake of boron by the tumor and irradiation with thermal neutrons. Phenylalanine is an amino acid precursor of melanin and when boronated (p-boronophenylalanine [BPA]) was found to be selectively taken up by Greene melanoma cells in the anterior chamber of rabbits. This tumor model was irradiated 24 hr ...

The effect of neutron boron capture therapy (BNCT) was studied in rat tumor liver cells after induction of the liver metastases by splenic inoculation of cells from DHA/K12/TRb line. Ten days following the treatment, the BPA was injected into rats and therefore the animals were sacrificed, the liver was exposed to neutron irradiation and processed. In some experiments the liver was reimplanted ...

Introduction: Neutrons have many applications in various fields, such as medicine. The important application of neutron in medical science is in Boron Neutron Capture Therapy (BNCT). Because of this, determination of neutron dose and flux is critical for the health maintaining of workers and patients exposed to this beam. The neutron radioisotope sources produce gamma rays in ...

Phantom experiments to evaluate thermal neutron flux distribution were performed using the Scintillator with Optical Fiber (SOF) detector, which was developed as a thermal neutron monitor during boron neutron capture therapy (BNCT) irradiation. Compared with the gold wire activation method and Monte Carlo N-particle (MCNP) calculations, it was confirmed that the SOF detector is capable of measu...

The 1MW pool-type Portuguese research reactor (RPI) was converted from using highly enriched uranium (HEU) to using low enriched uranium (LEU) fuel in September 2007. Although the new LEU core has the same number of fuel assemblies as the first HEU core, it has three assemblies less than the last HEU core and also has a different arrangement of the beryllium reflectors. Therefore, the primary i...