Miliaria is a disorder of the eccrine sweat glands which occurs in conditions of increased heat and humidity. It can be associated with persistent febrile states as well as with certain drugs. We presented a 40 year-old female with myelodysplastic syndrome and progression to acute myelogenous leukemia who was admitted to the hospital for chemotherapy induction. The patient was treated with idar...

Previous studies have demonstrated a marked reduction of haematological and non-haematological toxicity if weekly doses of docetaxel <40 mg/m2 were used. Reviewing the literature, neutropenic enterocolitis is uncommon but not unknown in patients treated with taxane-based chemotherapy. Although this complication occurs rarely, here we report on two patients, one with metastatic breast cancer and...

Patients receiving chemotherapy frequently develop fever and neutropenia. Haematopoietic growth factors (HGFs) may decrease the duration of such episodes or may prevent a febrile neutropenic episode. In this study we introduce a Markov type economic model for the hospital which calculates all relevant direct costs and savings of HGF therapy and may support decisions on HGF administration. A dis...

Neutropenic enterocolitis (NEC) has been widely reported in adults with myelofibrotic disorders, solid malignant tumors, bone marrow transplantation as well myelotoxic chemotherapy. Here we a case of 66-year-old non-diabetic, hypertensive female without any prior history immunosuppression or underlying malignancy related chemotherapy; who presented severe dyspnoea, low grade fever and cough. Fo...

background because of great concerns about mortality and morbidity of infection in febrile neutropenic patients, the appropriate empirical antibiotic should be started immediately. although there are established guidelines for the use of empirical therapy, local microbiological pattern and antibiotic susceptibility should be considered. objectives the current study aimed to identify the etiolog...

Comment Cusum plotting is clinically useful when a fever is swinging wildly and the overall trend is hidden, when other antimicrobial agents are given that are therapeutically unnecessary, and in patients in whom temperature remains raised but generally static. It indicates worsening of the fever despite antimicrobial treatment and thus discloses ineffective treatment. In this study the overall...

backgrounds: neutropenia can be associated with life-threatening infections. gram negative and staphylococcal infections are the most common pathogens. the spectrum of bacterial isolates has changed considerably over the past four decades. the objective of the present study was to evaluate the pattern of bacterial and fungal infections in neutropenic pediatric patients.   methods: a non-randomi...

Three chemotherapy-induced neutropenic hematologic patients with severe systemic infection caused by Fusobacterium nucleatum, a Gram-negative anaerobic rod, are described. Anaerobic infections are not very common in this patient category, but in a short period of time, several such patients were seen. The infection was considered to be caused by a combination of chemotherapy-induced mucositis, ...

Acute acalculous cholecystitis is a rare complication in the treatment of acute myeloblastic leukemia. Diagnosis of acute acalculous cholecystitis remains difficult during neutropenic period. We present two acute myeloblastic leukemia patients that developed acute acalculous cholecystitis during chemotherapy-induced neutropenia. They suffered from fever, vomiting and acute pain in the epigastri...