Sir, Naevus comedonicus was first described by Kofmann in 1895 (1). It was arranged in groups or linear patterns along Blaschko’s line and located on the face, neck, upper arms, chest and abdomen. It has been well documented that naevus comedonicus occurs as a single entity but occasionally in association with other disorders. The objective of this study was to analyse the clinical and immunohi...

173 I read with interest the article entitled “Multiple Large Cysts Arising from Nevus Comedonicus” by Jeong et al. [1]. I believe it is very difficult to cure nevus comedonicus (NC), as I have experienced performing repeated surgery for NC. The authors described a magnetic resonance imaging (MRI) scan that detected 5 cystic masses, but there were three resected masses and sets of physical find...

be associated with porokeratosis,[8] this diagnosis was not considered owing to the lack of typical clinical features and histology of this condition. Authentic clinical and histologic features of Nekam’s disease are, respectively,[9] a facial seborrheic dermatitislike eruption with tiny confluent papules on the trunk and extremities in linear and reticulate arrays and an infundibulocentric and...

Mutations in the fibroblast growth factor-receptor gene 2 (FGFR2) gene have been implicated in numerous diseases, including nevus comedonicus (NC) and naevoid acne that have somatic missense mutations in FGFR2 in the affected tissue. A patient presented in our department with unusual, innumerable large comedones throughout his back reminiscient of NC, as well as multifocal hidradenitis suppurat...