Whilemany studies of non-native species have examined either soft-bottom or hard-bottom marine communities, including artificial structures at docks andmarinas, formal comparisons across these habitat types are rare. The number of nonindigenous species (NIS) may differ among habitats, due to differences in species delivery (trade history) and susceptibility to invasions. In this study, we quant...

The non-invasive imaging and radiotherapy by sodium/iodine symporter (NIS) gene transfer have been widely used for many experiments and some clinical studies. Baculovirus is an efficient tool for gene delivery into mammalian cells in vitro and in vivo. However, the applications of NIS and/or baculovirus in nasopharyngeal carcinoma (NPC) cells have not been reported yet. In this study, two recom...

background:  little is known about trends and predictors of hardware related infection following open reduction and internal fixation (orif) of extremity fractures, one of the major causes of failure following orif. the present study was designed and conducted to determine trends and predictors of infection-related hardware removal following orif of extremities using a nationally representative...

The Mediterranean Sea is home to over 2/3 of the world's charter boat traffic and hosts an estimated 1.5 million recreational boats. Studies elsewhere have demonstrated marinas as important hubs for the stepping-stone transfer of non-indigenous species (NIS), but these unique anthropogenic, and typically artificial habitats have largely gone overlooked in the Mediterranean as sources of NIS hot...

The Na+/I- symporter (NIS) is important in hormone synthesis in the thyroid gland. NIS activity, as reflected by I- uptake, was increased by TSH (1 mU/mL) or forskolin (10 mumol/L) in primary cultured human thyroid cells. Northern blot analysis revealed that incubation of these cells with TSH or forskolin for 24 h increased the abundance of NIS messenger ribonucleic acid (mRNA) 2.3- and 2.5-fol...

UNLABELLED To evaluate the possibility of radionuclide gene therapy and imaging in hepatocellular carcinoma cancer, we investigated the iodine accumulation of a human hepatocellular carcinoma cell line, SK-Hep1, by transfer of human sodium iodide symporter (hNIS) gene. By targeting NIS expression in SK-Hep1, we could also investigate whether these cells concentrate 99mTc-pertechnetate and 188Re...

The current research is about the synthesis of pure nickel sulfide, a series Te (0, 0.5, 1, 1.5, 2, and 3 wt.%)-doped NiS (Te@NiS) nanoparticles (NPs), S-g-C3N4 (10, 30, 50, 70, 80 wt.%)/Te@NiS nanocomposites (NCs), fabricated through hydrothermal route. XRD FTIR spectroscopic techniques demonstrated successful NPs NCs. SEM-EDX images confirmed flakelike structure elemental constituents materia...

The BRAF V600E mutation causes impaired expression of sodium iodide symporter (NIS) and radioiodine refractoriness of thyroid cancer, but the underlying mechanism remains undefined. In this study, we hypothesized that histone deacetylation at the NIS (SLC5A5) promoter was the mechanism. Using the chromatin immunoprecipitation approach, we examined histone acetylation status on the lysine residu...

PURPOSE We recently reported the significant therapeutic efficacy of radioiodine therapy in various tumor mouse models following transcriptionally targeted sodium iodide symporter (NIS) gene transfer. These studies showed the high potential of NIS as a novel diagnostic and therapeutic gene for the treatment of extrathyroidal tumors. As a next crucial step towards clinical application of NIS-med...

The hypothesis that the human sodium-iodide symporter, NIS, can be used to detect NIS expression using standard radiological techniques was tested using adenoviral transduced NIS expression in human tumor xenografts grown in mice and in a naive dog prostate. Nonradioactive iodide was administered systemically to animals that 1-3 days previously had received a local injection of a replication-co...