background: normal salivary function is considered to be critical for the maintenance of healthy oral mucosa. oral fluids provide an easily available, non-invasive medium for the diagnosis of wide range of diseases and clinical situations. the objective of this study was to estimate and compare salivary nitric oxide levels in patients with oral lichen planus and healthy individuals. aim: to est...

Copper is one of the heavy metal in plant that causes toxicity at high concentration via producing reactive oxygen species. Nitric oxide can protect cells from oxidative stress produce by reactive oxygen species. Effect of different concentrations of copper (1000, 1500 and 2000 μM) and interaction with nitric oxide (100 and 150 μM) were studied on growth parameters (shoot and root length) and s...

objective(s): protein kinase c (pkcα) is involved in modulating articular chondrocytes apoptosis induced by nitric oxide (no). hyaluronic acid (ha) inhibits nitric oxide-induced apoptosis of articular chondrocytes by protecting pkcα, but the mechanism remains unclear. the present study was performed to investigate the effects and mechanisms of pkcα regulate protective effect of hyaluronic acid....

objective(s) single injection of naloxone, a selective antagonist of morphine, prior to the drug conditioning testing was used to investigate on morphine dependence. materials and methods conditioning to morphine (2.5-10 mg/kg, s.c.) was established in adult male wistar rats (weighing 200-250 g) using an unbiased procedure. nitric oxide agents were microinjected into the central amygdala prior ...

objective(s) celecoxib acts through both cox-2-dependent and -independent pathways. according to the paradoxical effect of no on the inflammatory and nociceptive signal processing, the present study designed to evaluate the probable contribution of no in the analgesic and anti-inflammatory properties of celecoxib. materials and methods different intensities of inflammatory pain were induced by ...

introduction: response to morphine and role of nitric oxide (no) on expression of morphine response has been studied in vertebrates. but, little evidence is provided in the matter in earlier invertebrates. this investigation for the first time evaluated the effect of no on expression of morphine potency in paramecium caudatum. methods: animal after isolation from natural media and specific iden...

diagnosis of subclinical and early stage clinical periodontal dysfunction could prevent from further socioeconomic burden. the aim of this study was to assess the diagnostic applicability of nitric oxide and its end-metabolites in periodontal tissue health and disease. forty-two patients were enrolled and divided into three groups according to gingivitis (gi) and clinical attachment level (cal)...

this experiment was conducted to evaluate the effects of supplemental l-arginine (arg) in reduced-protein diets on cardiopulmonary performance and intestinal morphology in the broilers reared at high altitude. a total of 156 day-old male broilers were randomly assigned to 3 treatments and 4 replicates of 13 chicks and reared up to 42 days of age. treatment groups were designed as a normal-prote...

Seedling greening upon irradiance is essential for the survival of plant after germination. Here, we studied role nitric oxide (NO) in regulating accumulation chlorophyll during Arabidopsis seedlings, and also investigated changes ATP chloroplast cytoplasm by using a fluorescent protein sensor (Ateam 1.03-nD/nA) based on fluorescence resonance energy transfer (FRET) effects NO content. The resu...

objective(s):the neuropeptide calcitonin gene-related peptide (cgrp) has long been postulated to play an integral role in the pathophysiology of migraine. earlier studies showed that cgrp can stimulate the synthesis and release of nitric oxide (no) and cytokines from trigeminal ganglion glial cells. the purpose of this study was to determine the effect of 17β-estradiol in regulation of cgrp exp...