BACKGROUND Fatty acids are substantial components of lipids and cell membranes in the form of phospholipids. This review consists of two parts. The present part aims at describing fatty acid classification, dietary sources and biological functions. The second part will focus on fatty acid physiological roles and applications in human health and disease. RESULTS In humans, not all fatty acids ...

After incubation, the triacylglycerol-rich lipoproteins seen under the electron microscope appeared as partially degraded structures with atypical, discoid, flattened and lamellar forms. As shown in Table 1, heparin produced a significant increment in the hydrolysis of 3H-labelled esterified fatty acids and 14C-labelled acylglycerol glycerol from the 3Hand 14C-labelled triacylglycerol-rich lipo...

1. The effect of infusion of noradrenaline (0.42 mumol min-1 kg-1) on the exchange of nonesterified fatty acids, glycerol and other metabolites across subcutaneous abdominal adipose tissue was investigated in five healthy subjects using an arteriovenous catheterization technique and measurement of adipose tissue blood flow using the 133Xe clearance technique. At the same time, the net rate of f...

Pregnancy is characterized by a complexity of metabolic processes that may impact fetal development and ultimately, infant health outcomes. However, our understanding of whole body maternal and fetal metabolism during this critical life stage remains incomplete. The objective of this study is to utilize metabolomics to profile longitudinal patterns of fasting maternal metabolites among a cohort...

I . Three sheep, each of which was fitted with a rumen cannula and with two pairs of reentrant cannulas in different parts of the small intestine, were used in this study. They were fed on dried grass cubes or hay plus linseed meal and oats: an aqueous solution of polyethylene glycol (PEG) was infused continuously into the rumen. 2. Total lipids were extracted from samples of the chyme entering...

The incorporation into triglycerides of l-14Clabeled saturated free fatty acids (FFA) of different chain lengths (CrC,,) was studied using incubation of rat epididymal fat pads in vitro. The results indicate that the rate at which adipose tissue incorporates FFA is dependent on chain length. With very short-chain acids a small amount is directly esterified into triglycerides, but the major port...

Replacement of dietary triglycerides containing long-chain fatty acids (LCFA) by triglycerides containing medium-chain fatty acids (MCFA) markedly reduced the capacity of alcohol to produce fatty liver in rats. After 24 days of ethanol and MCFA, the increase in hepatic triglycerides was only 3 times that of controls, whereas an 8-fold rise was observed after ethanol and LCFA. The triglyceride f...