Background Chronic stress is implicated in the development of various psychiatric illnesses including major depressive disorder. Previous reports suggest that patients with major depressive disorder have increased levels of oxidative stress, including higher levels of DNA/RNA oxidation found in postmortem studies, especially within brain regions responsible for the cognitive and emotional proce...

BACKGROUND Epidemiologic evidence suggests that chronic stress may alter susceptibility to air pollution. However, persistent spatial confounding between these exposures may limit the utility of epidemiologic methods to disentangle these effects and cannot identify physiologic mechanisms for potential differential susceptibilities. OBJECTIVES Using a rat model of social stress, we compared re...

A large scale survival chamber was developed as a screen for detecting chemical treatments that extend the survival time of illuminated soybean seedlings at CO(2) concentrations below the compensation point. In theory, extended survival should indicate potential for improved crop performance via decreased photorespiration and increased photosynthetic efficiency. An automated control system regu...

BACKGROUND Severely stressful early experiences have been implicated in the pathophysiology of psychiatric disorders. In contrast, exposure to mild early life stress (i.e., stress inoculation) strengthens emotional and neuroendocrine resistance to subsequent stressors. Herein we extend this research to examine the effects of mild early life stress on cognition. METHODS Squirrel monkeys were r...

This paper studies the risk of intrauterine growth restriction (IUGR) using support vector machines (SVM). A structured and globally optimized SVM system may be preferable procedure in the identification of IUGR fetus at risk. The IUGR risk is estimated in two stages: in the first stage, noninvasive Doppler pulsatility index (PI) and resistance index (RI) of umbilical artery (UA), middle cerebr...

The case: A previously healthy 37-year-old woman (gravida 3, para 1 with 2 first-trimester miscarriages) had an unremarkable pregnancy until the 35th week. Her blood pressure readings during pregnancy were between 100/70 mm Hg and 110/80 mm Hg. She had no previous seizure disorders or hypertension. At week 28, gestational diabetes was diagnosed by means of an oral glucose tolerance test and sub...

BACKGROUND The aim of this study was to compare the biophysical profile parameters (BPP), especially amniotic fluid index (AFI), before and after administration of corticosteroids (dexamethasone and betamethasone) and these two groups with each other. MATERIALS AND METHODS This double-blind clinical trial study was done on 70 patients for 28-34 weeks women having at least one preterm labor in...

INTRODUCTION It is estimated that 3-10% of infants are growth restricted. Growth disturbances may have long-term issues. Doppler allows insight into the fetal response to intrauterine stress. OBJECTIVE The aim of this study was to detect fetal compromise in intrauterine growth-restricted (IUGR) fetuses by means of biophysical profile (BPP) vis-à-vis Doppler velocimetry studies of the fetal um...