Oxygen delivery and consumption after hemodilution with a perfluorocarbon-based oxygen carrier (PFCOC) was evaluated at sea level and at 2,600 m above sea level. Fifteen anesthetized rats were subjected to a two-exchange normovolemic hemodilution of 40% of the circulating blood volume each. First exchange was performed with a colloid solution. Second exchange was with 80% PFCOC and 20% colloid....

BACKGROUND AND OBJECTIVES Acute Normovolemic Hemodilution (ANH) is a simple and low-cost autologous transfusion method. This study aimed at evaluating whether ANH is able to decrease homologous transfusions in children undergoing posterior spinal fusion and at verifying hemodilution-induced complications in those patients. METHODS Participated in this study 25 children, physical status ASA I ...

Guinea pig cochlear blood flow was measured before and after systemic normovolemic hemodilution with high molecular weight dextran. Absolute determinations of blood flow (in the cochlea, brain, kidney and lung) were accomplished by use of radioactive-labeled (85Sr or 141Ce) microspheres. Relative measurements of the cochlear blood flow changes were made simultaneously by the use of a laser Dopp...

Significant progress has been made in the development of oxygen-carrying hemoglobin solutions for therapeutic use. Religious objection to donor red blood cells in the setting of perioperative blood loss and anemia is one of several potential uses of these products. Here we present a case in which a polymerized hemoglobin solution was used on a compassionate care basis to augment acute normovole...

BACKGROUND Preoperative autologous blood donation is accepted as a standard of care for radical prostatectomy. Acute normovolemic hemodilution (ANH) is an alternative method for obtaining autologous blood. The cost and benefits of these two autologous blood-collection techniques are compared. STUDY DESIGN AND METHODS Thirty consecutive patients scheduled for radical prostatectomy underwent AN...

Hemodilution is one of the sequelae of cardiopulmonary bypass (CPB). Autologous blood priming (retrograde autologous priming [RAP]/venous antegrade priming [VAP]) and acute normovolemic hemodilution (ANH) may be effective techniques to minimize hemodilution. The primary objective of this study is to investigate the impact of RAP/VAP combined with ANH on changes in cerebral saturations. A retros...

Autologous blood transfusion is an endorsed blood conservation strategy that has become widely practiced in elective surgical procedures. We review ten years' experience in this arena, along with emerging strategies designed to continue to minimize allogeneic blood exposure but reduce the costs associated with autologous blood procurement. We conclude that point-of-care autologous blood procure...

Autologous blood transfusion (ABT) has been gradually attracting more attention due to the increasingly prominent problem of blood transfusion safety and blood shortage in recent years. With the rapid development of blood conservation techniques, blood component separation technology, blood transfusion medicine and a constant increase in clinical needs, ABT technology has been expanded and inno...