OBJECTIVES To describe the association between fear of childbirth and social, demographic and psychological factors in a cohort of 30 480 healthy nulliparous women with uncomplicated singleton pregnancies. DESIGN Nationwide population-based study. SETTING The Danish National Birth Cohort. POPULATION Healthy nulliparous women (n= 30 480) with singleton pregnancies. METHODS Data from comp...

Many epidemiologic and clinical studies have indicated that the frequency of breast cancer was lower in parous women than in nulliparous women. Moreover, the incidence of breast cancer has been reported to be lower in women with early childbirth than in women with late childbirth. To verify the effect of childbirth and the age at first childbirth on carcinogenesis and progression of breast canc...

The objective of this study was to comprehensively compare the genomic profiles in the breast of parous and nulliparous postmenopausal women to identify genes that permanently change their expression following pregnancy. The study was designed as a two-phase approach. In the discovery phase, we compared breast genomic profiles of 37 parous with 18 nulliparous postmenopausal women. In the valida...

Q1. From the methodology section it’s not quite clear whether nulliparous women younger than 30 years old were “excluded” or “not included”? The total of 482 “who approached” (from the results section) – was this the figure after excluding nulliparous and pregnant women or before exclusion? If after the exclusion –than the nulliparous women <30 y.o and pregnant “were not included”. In other wor...

BACKGROUND In women with rheumatoid arthritis (RA) it has been observed that during pregnancy a majority of patients experience amelioration, but after delivery a relapse of the disease is common. However, there are few studies, with diverging results, addressing the effect of parity on the severity of RA over time. Our aim was to explore the impact of parity, with stratification for anti-citru...