Currently, basal ganglia (BG) are considered regulators of motor and emotional activity. It's operationality encompass Obsessive Compulsive Disorder (OCD). The case of a patient suffering with severe OCD is described of note, his symptoms disappeared following a hemorrhage of the left BG. However, once the hemorrhage was reabsorbed his symptoms returned. It is possible that lesions affecting ce...

abstract background and aim: the intolerance of uncertainty model was initially developed as an explanation for worry within the context of generalized anxiety disorder. however, recent research has identified intolerance of uncertainty (iu) as a transdiagnostic maintaining factor across the anxiety disorders. the aim of the present study was to compare the intolerance of uncertainty in patient...

Parents of autistic probands with high and low rates of repetitive behaviors were compared for rates of obsessive-compulsive traits and disorder. The rate of repetitive behaviors was assessed using the Autism Diagnostic Interview-Revised (ADI-R) in 176 autistic probands from 57 multiplex families. Obsessive-compulsive disorder (OCD) in parents was determined by direct interview using a parental...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...

objective: the present study aimed to explore the relationship between worry and obsessive compulsive symptoms. we examined the correlations between the padua inventory (pi) and the penn state worry questionnaire (pswq) to further explore the distinctiveness of the pi. method: seventy-five subjects (n=40 male, n= 35 female) were selected from hafez hospital (iran) for this study: the subjects i...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...

Glutamatergic hyperactivity hypothesis in obsessive-compulsive disorder (OCD) has been proposed but not tested. Memantine is an uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist. We report two cases of refractory obsessive-compulsive disorder treated with an augmentation of memantine at 15 mg/day. The first case did not benefit from such treatment, while the second showed immediate ...

AIM To review available evidence on the use of cognitive behavioural therapy (CBT) for treating obsessive compulsive disorder co-occurring with psychosis. METHODS In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder (OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relev...