T he syndrome of sleep apnea has been described throughout the ages, dating at least to descriptions of Dionysius the Tyrant in the fourth century BC. It is only recently that scientific investigation has led to an understanding of this previously ill-defined syndrome. Sleep apnea is the currently accepted term for a group of heterogeneous sleep-associated respiratory disorders. The most common...

OBJECTIVE To examine whether circulating leptin levels correlate with the severity of disease in patients with obstructive sleep apnea. DESIGN Prospective nonrandomized study. SETTING Referral sleep laboratory for patients with sleep-disordered breathing and biochemistry laboratory. Patients Thirty-two subjects (mean +/- SD age, 47 +/- 12 years) who were referred for suspected sleep apnea u...

OBJECTIVES While respiratory distress is accepted as the only indication for diaphragmatic plication surgery, sleep disorders have been underestimated. In this study, we aimed to detect the sleep disorders that accompany diaphragm pathologies. Specifically, the association of obstructive sleep apnea syndrome with diaphragm eventration and diaphragm paralysis was evaluated. METHODS This study ...

BACKGROUND Sleep related disordered breathing (SDB) in pediatric Prader-Willi Syndrome is gaining increased attention due to the possible association of growth hormone therapy, SDB and sudden death. However data on the patterns of SDB and their management, particularly in infants in this population, is lacking. OBJECTIVE The aim of this study was to 1) describe patterns of SDB in growth hormo...

OBJECTIVE Obstructive sleep apnea syndrome is associated with cardiovascular diseases and thromboembolic events. The mean platelet volume (MPV) is a predictor of cardiovascular thromboembolic events. The aim of the present study is to investigate the association between the MPV and disease severity in patients with obstructive sleep apnea syndrome. METHODS We prospectively included 194 obstru...

The obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common disorder, estimated to occur in 4% of males and 2% of females in the workforce. This incidence increases with age. Obstructive sleep apnea-hypopnea is responsible for acute and chronic heart disease, but is a readily treatable disorder that is both underdiagnosed and underappreciated in health care. Because the cardiac consequenc...

INTRODUCTION Sleep movement disorders includes mainly periodic limb movement and others. The more frequent breathing disorders are: obstructive sleep apnea-hypopnea syndrome and primary snoring. OBJECTIVE To compare sleep architecture in periodic limb movements and breathing disorders of different severity, and weight their interactions. METHODS We compared sleep architecture in 160 patient...

AIM The aim of the Danish National Database for Obstructive Sleep Apnea (NDOSA) was to evaluate the clinical quality (diagnostic, treatment, and management) for obstructive sleep apnea and obesity hypoventilation syndrome in Denmark using a real-time national database reporting to the Danish National Patient Registry. STUDY POPULATION All patients diagnosed with obstructive sleep apnea or obe...

background and objective: obstructive sleep apnea (osa) is the most common type of sleep-disordered breathing. multivariable apnea prediction (map) index consists of three questions about the frequency of osa symptoms plus body mass index (bmi), age and sex that categorizes the patients to low and high risk for osa using a formula. objective map index was calculated by discounting the questions...