OBJECTIVES We compared intravascular ultrasound (IVUS) and 2 different generations of optical coherence tomography (OCT)-time-domain OCT (TD-OCT) and frequency-domain OCT (FD-OCT)-for the assessment of coronary disease and percutaneous coronary intervention (PCI) using stents. BACKGROUND OCT is a promising light-based intravascular imaging modality with higher resolution than IVUS. However, t...

Members of the Oct family of transcription factors specifically interact with the octamer motif, ATGC-AAAT, a regulatory element important for tissue- and cell-specific transcription as well as for the expression of housekeeping genes. Except for Oct-1, all Oct factors are expressed in a temporally and spatially restricted mode during murine development and their number varies in a given cell t...

BACKGROUND/AIMS Choroidal thickness measurements are reported to differ between spectral-domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT). The aim of this study was to assess the comparability of choroidal thickness measurements using SS-OCT and SD-OCT devices among normal participants. MATERIALS AND METHODS This was a prospective study of 31 (62 eyes) normal partici...

PURPOSE The integration of swept-source optical coherence tomography (SS-OCT) into the operating microscope enables real-time, tissue-level three-dimensional (3D) imaging to aid in ophthalmic microsurgery. In this prospective randomized controlled study, we evaluated the impact of SS microscope-integrated OCT (MI-OCT) on ophthalmology residents' performance of ophthalmic microsurgical maneuvers...

Octreotide (OCT) can inhibit tumor growth with few side‑effects. In this study, we hypothesized that an OCT- and poloxamer 407 (P407)-based temperature‑sensitive gel may compensate for the short half‑life of OCT, which may thus lead to the development of a novel therapy for patients with end‑stage liver cancer by intratumoral injection. The proliferation and apoptosis of mouse Hca‑F hepatocellu...

PURPOSE To evaluate the sensitivity and specificity of machine learning classifiers (MLCs) for glaucoma diagnosis using Spectral Domain OCT (SD-OCT) and standard automated perimetry (SAP). METHODS Observational cross-sectional study. Sixty two glaucoma patients and 48 healthy individuals were included. All patients underwent a complete ophthalmologic examination, achromatic standard automated...

purpose: to measure peripapillary retinal nerve fiber layer (rnfl) thickness in normal human eyes by optical coherence tomography (oct). methods: eighty-one eyes of 45 normal participants were studied. each person underwent a complete ophthalmic examinations, including measurement of visual aquity and intraocular pressure and evaluation of the anterior segment, optic disc, and retinal nerve fib...

POU domain transcription factor Oct-4 plays a crucial role in maintaining self-renewal and pluripotency of embryonic stem (ES) cells in a concentration-dependent manner. However, the molecular mechanism controlling Oct-4 levels in ES cells remains largely unknown. To explore the molecular mechanism regulating Oct-4 function, we constructed a mouse ES cell cDNA library and performed yeast two-hy...

Optical coherence tomography (OCT) is an imaging of any tissue we can analyze with a light source [1], OCT became the gold standard for retinal disease during the last decade and take the most important place in multimodal exploration in retinal diseases. Time domain OCT (TD OCT) first, spectral domain OCT (SD OCT) and swept source OCT (SS OCT) now, are the best friends for the retinal daily pr...

GnRH (gonadotropin-releasing hormone) plays a pivotal role in the regulation of reproduction in vertebrates through interaction with a specific receptor. Previously, we isolated a GnRH homologue, oct-GnRH, from the common octopus (Octopus vulgaris). In the present study, we have identified a GnRH receptor (oct-GnRHR) specific for oct-GnRH from Octopus brain. Oct-GnRHR includes domains and motif...