Young adult binge drinkers represent a model for endophenotypic risk factors for alcohol misuse and early exposure to repeated binge cycles. Chronic or harmful alcohol use leads to neurochemical, structural and morphological neuroplastic changes, particularly in regions associated with reward processing and motivation. We investigated neural microstructure in 28 binge drinkers compared with 38 ...

developmentprogress.org This and other Development Progress materials are available at developmentprogress.org Development Progress is an ODI project that aims to measure, understand and communicate where and how progress has been made in development. ODI is the UK’s leading independent think tank on international development and humanitarian issues. Further ODI materials are available at odi.o...

BACKGROUND The purpose of this study was to compare the efficacy of percutaneous kyphoplasty (PKP) and bone cement-augmented short segmental fixation (BCA+SSF) for treating Kümmell disease. MATERIAL AND METHODS Between June 2013 and December 2015, 60 patients were treated with PKP or BCA+SSF. All patients were followed up for 12-36 months. We retrospectively reviewed outcomes, including Oswestr...

Objectives To quantify and compare the match demands variability of international One-Day (ODI) with Twenty20 (T20) cricket matches to ODI when competing home away. Design Single cohort, longitudinal observation. Methods Thirteen male seam bowlers across 204 (ODI = 160; T20 44) were investigated over five-years (2015−2019). Using global positioning sensors accelerometers, physical quantified us...

Abstract Study Objectives Respiratory sleep indices are traditionally reported on the basis of average total time. The relationship between hour-to-hour variability these parameters and blood pressure (BP) has not been reported. Methods We evaluated associations apnea–hypopnea index (AHI), oxygen desaturation (ODI), lowest saturation with 24-hour ambulatory BP in patients hypertension newly dia...

Background & Aim: To assess functionality status and surgical outcome of fenestration versus laminotomy technique based on Core Outcome Measures Index (COMI) in patients with lumbar disc hernia (LDH). Methods & Materials/Patients: A cross-sectional study was performed between January 2007 and April 2012. A total of 108 patients with a single-level disc herniation were asked to respond to the...

Advancements in data technology provide easy access to open sets that can act as raw material promote competencies the education domain. In this study, we investigate how be used develop digital and literacy skills among secondary school students (ages 11–15). Using qualitative quantitative research methods, identify collection analysis integrated into using openly available sets. We also test ...

The aims of this study were; 1) to develop the final version of the Korean Roland-Morris Disability Questionnaire (RDQ), and 2) to compare the responsiveness between the RDQ and the Oswestry Disability Index (ODI) scores in patients having low back pain. The psychometric properties of the final Korean RDQ were evaluated in 221 patients. Among them, 30 patients were reliability tested. Validity ...

Systemic hypertension is associated with obstructive sleep apnoea syndrome (OSAS) but the pathophysiological mechanisms are incompletely understood. A collaborative European network of 24 sleep centres established a European Sleep Apnoea Database to evaluate cardiovascular morbidity associated with OSAS. 11 911 adults referred with suspected OSAS between March 2007 and September 2013 underwent ...