INTRODUCTION — Prior to the development of modern cardiovascular surgery, most cases of mediastinitis arose from either esophageal perforation or from contiguous spread of odontogenic or retropharyngeal infections. Rarely, primary infections of the mediastinum developed as a result of penetrating trauma or hematogenous spread of infection. However, in modern practice, most cases of mediastiniti...

Background. Treatment of odontogenic infections includes surgical drainage and adjunctive antibiotics. This study was designed to generate efficacy and safety data to support twice daily dosing of amoxicillin/clavulanic acid compared to clindamycin in odontogenic infections. Methods. This was a phase IV, randomised, observer blind study; 472 subjects were randomised to receive amoxicillin/clavu...

AIMS An evaluation is made of bacterial species and susceptibility to various antibiotics used in application to odontogenic infections of periapical location and in pericoronitis of the lower third molar, with the aim of optimizing the antibiotherapy of such infections and thus preventing unnecessary side effects and over-treatment. MATERIAL AND METHODS Sixty-four patients with odontogenic i...

Introduction: Descending necrotizing mediastinitis is a rare complication of odontogenic infections, with a high mortality rate despite the advent of antibiotics. case report: An otherwise well 37-year-old male presented with descending necrotizing mediastinitis secondary to a mandibular second molar infection. He required prolonged targeted antibiotic treatment, extensive oral, neck and thorac...

Odontogenic infections lead to life-threatening complications once they reach potential fascial spaces due to decreased immunity in pregnancy. It may also occur due to patient negligence, delayed diagnosis and mismanagemnet. Infratemporal space infection is a rare but a serious sequel of odontogenic infection. We report the case of a 20 year old, four months pregnant patient with carious left m...

Thrombocytopenia in surgical patients is a potentially serious condition,faced by surgeons. A close relationship between sepsis and thrombocytopenia has been suggested. Thrombocytopenia has even been suggested to be indicative of an acute infection. Platelet count in a septicemic patient may also serve as a prognostic tool. There are many reports of thrombocy-topenia due to septicemia in the li...

SummaryFour cases of oro-facial infection leading to life-threatening complications are reported. Although all had been treated with antibiotics prior to consultation, lack of surgical intervention had allowed the infection to progress. These cases are a reminder that acute spreading odontogenic infection can be life-threatening. Definitive treatment includes airway management, adequate resusci...

* Reader, Department of Oral and Maxilofacial Surgery, Harsaran Das Dental College, Ghaziabad, Uttar Pradesh, India ** Senior Lecturer, Department of Oral and Maxillofacial Pathology, Harsaran Das Dental College, Ghaziabad, Uttar Pradesh, India *** Reader, Department of Orthodontics, Krishna Dental College, Ghaziabad, Uttar Pradesh, India ________________________________________________________...