T o restore skeleton function in the fi eld of orthopaedic and oral-maxillofacial surgery, bone tissue regeneration remains an important challenge. Spinal fusion, augmentation of fracture healing, and reconstruction of bone defects resulting from trauma, tumour, infections, biochemical disorders, or abnormal skeletal development are clinical situations in which surgical intervention is required...

On April 18 2000, one of the largest takeovers in the pulp and paper industry took place. Through a dual cash-share exchange transaction, Donohue Inc. and Abitibi-Consolidated Inc. merged to form the largest newsprint producer in the world. The purpose of this clinical study is to analyse the incentives of all key stakeholders who were involved in the transaction: stockholders, directors, execu...

We investigated the effects of S1P3 deficiency on the age-related atrophy, decline in force, and regenerative capacity of soleus muscle from 23-mo-old male (old) mice. Compared with muscle from 5-mo-old (adult) mice, soleus mass and muscle fiber cross-sectional area (CSA) in old wild-type mice were reduced by ~26% and 24%, respectively. By contrast, the mass and fiber CSA of soleus muscle in ol...