نتایج جستجو برای: oncolysis
تعداد نتایج: 455 فیلتر نتایج به سال:
Some viral strains of the Paramyxoviridae family may be used as anti-tumor agents. Oncolytic paramyxoviruses include attenuated strains of the measles virus, Newcastle disease virus, and Sendai virus. These viral strains, and the Sendai virus in particular, can preferentially induce the death of malignant, rather than normal, cells. The death of cancer cells results from both direct killing by ...
The oncolytic properties of a new Clostridium strain 01 originating from pig skin extracts have been studied. The specificity toward various animal tumors of a typical pig skin fraction, spore-containing punctates of lysing tumors, and pure spore suspensions proved to be comparable. Several different kinds of transplanted tumors can be destroyed. The activity against spontaneous or induced tumo...
Cell adhesion molecules of the immunoglobulin superfamily are aberrantly expressed in malignant glioma. Amongst these, the human poliovirus receptor CD155 provides a molecular target for therapeutic intervention with oncolytic poliovirus recombinants. Poliovirus has been genetically modified through insertion of regulatory sequences derived from human rhinovirus type 2 to selectively replicate ...
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