Receiver operating characteristic (ROC) curves evaluate the discriminatory power of a continuous marker to predict a binary outcome. The most popular parametric model for an ROC curve is the binormal model, which assumes that the marker, after a monotone transformation, is normally distributed conditional on the outcome. Here, the authors present an alternative to the binormal model based on th...

Receiver operating characteristic (ROC) curve has been widely used in medical science for its ability to measure the accuracy of diagnostic tests under the gold standard. However, in a complicated medical practice, a gold standard test can be invasive, expensive, and its result may not always be available for all the subjects under study. Thus, a gold standard test is implemented only when it i...