Background and Aims: Different kinds of adjutants are used with local anesthetics during intrathecal procedure for prolongation of action. However, they are not completely free from side effects. Fascia Iliaca Compartment Block (FICB) is useful for the same purpose. Method: After administering 20ml 0.5% injection Bupivacaine in FIC (Fascia Iliaca Compartment) on the fractured side before anesth...

BACKGROUND Epidural analgesia is considered one of the most effective methods for pain relief during labor. However, it is not clear whether similar effects of epidural analgesia on the progression of labor, modes of delivery, and perinatal outcomes exist between nulliparous and multiparous women. METHODOLOGY/PRINCIPAL FINDINGS A retrospective cohort study was conducted to analyze all deliver...

conclusions this study showed that the addition of intrathecal magnesium sulfate to bupivacaine is not desirable in patients undergoing cesarean section due to the delay in the onset of sensory blockade and the lack of significant effects of magnesium on post-operative pain. results the onset of sensory blockade was delayed in case group compared with control group, and this was statistically s...

We studied the analgesic efficacy of tramadol 2 mg kg(-1) for post-operative analgesia after day-case adenoidectomy in children aged 1-3 yr. Eighty children were allocated randomly to receive tramadol 2 mg kg(-1) i.v. or placebo immediately after induction of anaesthesia. Anaesthesia was induced with alfentanil 10 microg kg(-1) and propofol 4 mg kg(-1) followed by mivacurium 0.2 mg kg(-1) for t...

BACKGROUND AND AIMS Local infiltration of the surgical wound is one of the important components of multimodal analgesia for post-operative pain relief. This study determines the post-operative analgesic effect of addition of dexmedetomidine to bupivacaine for local infiltration of the surgical wound. METHODS Sixty women belonging to American Society of Anesthesiologists' Grade 1 or 2 posted f...

The ischemia necrosis of limb frequently requires surgery of amputation. Lumbar plexus and sciatic nerve block is an ideal intra-operative anesthetic and post-operative antalgic technique for patients of amputation, especially for high-risk patients who have severe cardio-cerebrovascular diseases. However, the duration of analgesia of peripheral nerve block is hardly sufficient to avoid the pos...

The aim of this study was to investigate the effect of the μ-opioid receptor gene (OPRM1) A118G polymorphism on the requirement for post-operative fentanyl analgesia in patients undergoing radical gastrectomy. One hundred and twenty-eight gastric cancer patients scheduled to undergo radical gastrectomy under general anesthesia were enrolled in the study. Post-operative, patient-controlled intra...

Background: Many intrathecal adjuvants are being used with local anesthetics to prolong the intraoperative anesthesia and postoperative analgesia. Clonidine buprenorphine known potentiate effects of anesthestics. Aims Objectives: This study was designed compare duration analgesia as well sensory motor block onset, hemodynamic changes, perioperative complications between clonidine when an adjuva...

Objective: The objective of the study was to compare effects dexmedetomidine versus midazolam-fentanyl on post-operative recovery, sedation, analgesia, and hemodynamic parameters in patients undergoing middle ear surgery under local anesthesia. Methods: Seventy-two were randomly divided into two equal groups - Group D (dexmedetomidine) MF (midazolam fentanyl). Intra operative heart rate, mean b...

background and purpose: this study was designed in order to compare the effects of spinal and epidural analgesia on labour and also several maternal and fetal factors in vaginal delivery. materials and methods: the study was a randomized clinical trail and participatnts were 120 gravid 1 and gravid 2 women in the active phase of delivery, admitted to the labour room of fatemieh hospital in hame...