Aschottana is one of the speciality procedures among kriyakalpas in which herbal medications form liquid are instilled into conjunctival sac, drop by at a distance 2 angulas called as Aschottana. Ocular drugs usually delivered locally to eye. Required drug loading, release rate, and ocular retention time delivery systems depend on potency, bioavailability, clearance target site. The concept exp...

Microemulsions, comprising oil, water and a surfactant, in association with some co-surfactant, are thermodynamically stable systems. They have found applications large number of chemical pharmacological processes due to their unique properties such as interfacial area, low tension, most importantly, the ability solubilize deliver hydrophobic drugs. In addition oral intravenous route, they suit...

The poor retention and efficacy of instilled drops as a means of delivering drugs to the ophthalmic environment is well-recognised. The potential value of contact lenses as a means of ophthalmic drug delivery, and consequent improvement of pre-corneal retention is one obvious route to the development of a more effective ocular delivery system. Furthermore, the increasing availability and clinic...

Poor bioavailability is one of the most significant problems in delivery ocular drug system. Ophthalmic ointments, solutions and suspensions are frequently used dosage forms to treat disease, their effectiveness as a compromised by several limitations that lead poor bioavailability. In situ gel promising strategy improve drugs. The purpose this review discuss formulation characterization gel. T...

Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited by physiological conditions. The use of nonionic or ionic biodegradable polymers in aqueous solutions and colloidal dosage forms such as liposomes, nanoparticles, nanocapsules, ...

Voriconazole (VRC) incorporated in composited polyvinyl alcohol (PVA)/hydroxypropyl-β-cyclodextrin (HPβCD) blended nanofibers were produced via electrospinning for efficient ophthalmic delivery. The VRC loading capacity increased with increasing HPβCD content. The optimal solution for electrospinning consisted of 8% (w/v) PVA, 4% (w/v) HPβCD and 0.5% (w/v) VRC. The nanofibers exhibited bead-fre...

BACKGROUND To assess the utilization of and satisfaction with ophthalmic healthcare provided by integrated delivery system (IDS) since 2000 and vision-related quality of life (VRQoL) for residents of an offshore island of Taiwan. METHODS Facilitators interviewed residents (age ≥ 50 years) with the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) for VRQoL and a questi...