Both chronic pain and prescription opioid abuse are prevalent and continue to exact a heavy toll on patients, physicians, and society. Individuals with chronic pain and co-occurring substance use disorders and/or mental health disorders, are at a higher risk for misuse of prescribed opioids. Opioid abuse and misuse occurs for a variety of reasons, including self medication, use for reward, comp...

Given the increase of opioid dependence and opioid-related morbidity and mortality, improving treatment options for individuals with opioid dependence warrants increased attention. This article provides a concise review of work in this area. Remission from opioid dependence can be very difficult to sustain, particularly in the absence of opioid replacement or opioid antagonist therapy. For thos...

Background Harm reduction, practices that reduce the harms associated with substance abuse without necessarily reducing drug use or consumption, may be a successful strategy to decrease drug-overdose deaths.Types of Studies Reviewed Article reviewed studies and policies focused on harm prescription opioid abuse, medical-dental integration, factors contributing rise in opioid-related deaths.Resu...

background: informal employment is common in developing countries, including egypt. this type of employment may have significant consequences on mental health. objectives: to determine the prevalence and risk factors of common mental disorders and substance abuse among temporary hired hospital cleaners. methods: a cross-sectional study was conducted on 242 adult temporary cleaners and 209 perma...

conclusions the results of this study in terms of personality disorders and types of used drugs were in accordance with the previous studies results. it is necessary to design appropriate treatment plans for medical treatment of those with personality disorders. results there was a significant correlation between stimulant use and histrionic personality disorder (p < 0.001) and antisocial and n...

BACKGROUND Opioids are frequently used for the postoperative treatment of chronic disabling occupational musculoskeletal disorders. In many such cases, long-term opioid use persists because of patient requests for ongoing pain relief. Little is known about the relationship between chronic opioid use and functional recovery in these patients. METHODS A total of 1226 patients with a chronic dis...

The idea that learning proceeds as a function of the discrepancy (or error) between expected and obtained outcomes is central to many theories of associative learning. However, remarkably little is known about the neurobiological mechanisms that underlie this learning of predictive errors in fear conditioning, a widely used preparation in studies of cellular and molecular mechanisms of memory. ...

OBJECTIVE The prevalence of opioid therapy for chronic noncancer pain has increased dramatically in recent years, with a parallel increase in opioid abuse, misuse and deaths from accidental overdose. We review epidemiological and clinical data that point to the important roles psychiatric disorders have in the use and abuse of opioids in patients with chronic pain. METHOD We conducted literat...

An increase in illicit drug use in Northern Ireland may well have links to the resolution of political conflict, which started in the mid 1990s. Social issues, heretofore hidden, have emerged into the limelight and may be worsened by paramilitary involvement. Registered addicts in the four Health Board areas have shown an increase from 1997 with the greatest number resident within the Northern ...

BACKGROUND Psychiatric disorders may affect patients suffering from cancer and substance use disorders. OBJECTIVE This study was undertaken to evaluate the prevalence of tobacco and opioid use in patients with gastric cancer in Shiraz, Fars Province and Southern Iran. MATERIALS AND METHODS In a hospital survey of 177 gastric cancer patients aged 24 years and more, a semistructured-interview...