Young axons of new retinal ganglion cells (RGCs) in the continuously growing goldfish retina fasciculate with one another and their immediate forerunners on their path toward the optic disk and along the optic nerve. They express the immunoglobulin superfamily cell adhesion molecules (CAMs) neurolin (DM-GRASP) and the L1-like E587 antigen. Repeated injections of Fab fragments from polyclonal an...

A micro-oxygen sensor was used to monitor the optic-disk oxygen tension in vivo in the cat. The perfusion pressure of the eye, defined as the systemic arterial blood pressure minus the intraocular pressure, was decreased. This was accomplished both by lowering the systemic arterial blood pressure by increasing the expiratory resistance and by elevating the intraocular pressure. The result of lo...

OBJECTIVE To compare the morphology of normal, healthy Gottingen minipig retinal vessels of the optic disk with experimentally induced glaucomatous optic disks in order to identify the glaucomatous excavation. Present results were compared to human glaucoma findings. PROCEDURE Sixteen eyes from eight Göttingen minipigs were studied using fundoscopic photography and fluorescein angiography. Ex...

A 37-year-old Bangladeshi male presented with an inferotemporal optic disk pit and serous macular detachment in the left eye. Imaging with spectral domain optical coherence tomography (OCT) revealed a multilayer macular schisis pattern with a small subfoveal outer retinal dehiscence. This case illustrates a rare phenotype of optic disk maculopathy with macular schisis and a small outer retinal ...

shading offers hope of dense depth measurements; however, it has to contend with the spatially varying albedo of the surface of the optic disk. Fortunately, we can control the lighting and positions of the stereo pair of cameras. Section 2 describes how we can exploit this degree of freedom to apply a technique akin to homomorphic filtering to separate the contribution of albedo and reflectance...

Arcuate scotomas and occasionally severe peripheral constriction of the visual field are familiar sequelae of drusen of the optic disk. Loss of central vision with this disk anomaly is rare and its occurrence always demands additional investigations. It has been a long established rule that monocular blindness cannot be attributed to the progressive neurovascular complications of optic disk dru...

A 51-year-old woman had optic disk cupping from optic nerve compression by an intracranial aneurysm. Slit-lamp stereoscopic examination of the living eye immediately post mortem revealed an optic cup vertically oral, elongated superiorly, and indistinguishable from disk changes seen early in glaucoma. The histopathological changes differed from those in glaucoma by showing no glial atrophy. Ins...