Peripheral blood glucose and immunologically reactive insulin levels were determined in freely moving normal rats which were submitted either to a free oral glucose load or to a gastric administration of the glucose load. Identical determinations were performed in ventromedial hypothalamic nucleus-(VMH) lesioned and vagotomized rats after the same oral intake. It was demonstrated that: 1) a fre...

Although widely assumed to have only satiating actions, nutrients in the gut can also condition increases in intake in some cases. Here we studied the time course of post-oral nutrient stimulation of ingestion in food-restricted C57BL/6J mice. In experiment 1, mice adapted to drink a 0.8% sucralose solution 1 h/day, rapidly increased their rate of licking (within 4-6 min) when first tested with...

Whether glucose concentration increases during heat exposure because of reduced peripheral tissue uptake or enhanced appearance is currently unknown. This study aimed to report concentrations in both capillary and venous blood response a challenge passive heating (PH) assess whether affects healthy males. Twelve male participants completed two experimental sessions, where they were asked undert...

background and objective: alleviation of serum glucose level and lipid profile in diabetic patients using herbal medications is of great importance. in the present study, the effect of oral consumption of olive leaves on serum glucose level and lipid profile was investigated. materials and methods: male wistar rats were divided into four groups including control, control under treatment, diabet...

background : magnesium is the second most abundant intracellular cation. it plays an important role in insulin homeostasis and glucose metabolism through multiple enzymatic reactions. with increasing data on magnesium deficiency in diabetic patients and epidemiological studies demonstrating magnesium deficiency as a risk factor for diabetes, it is logical to search for its possible beneficial e...

In patients with portal hypertension, plasma insulin levels were raised both fasting and after oral glucose or intravenous tolbutamide. This supports previous suggestions that resistance to endogenous insulin plays a major role in producing the impaired glucose tolerance found in chronic hepatic dysfunction. The operation of portacaval anastomosis was followed by impaired oral fructose toleranc...

as a supplement to the oral method has been pointed out by many workers. Moreover, the possibility of error in the result of oral method due to diminished absorption has been shown by Beeler, Bryan, Cathcart and Fitz (1922). The flat blood sugar curve obtained by Thaysen (1929) after the oral administration of glucose, as has been shown by the author, is due to the diminished absorption of gluc...

We herein describe the case of a 68-year-old man who developed overt diabetes mellitus following the topical administration of dexamethasone 0.1%-containing ointment over a five-month period to treat oral lichen planus. The topical dexamethasone therapy was discontinued gradually, and the patient was subsequently treated with insulin for one month without clinical signs of overt adrenal insuffi...