This study was designed to investigate the effect of two surfactants, dodecyl benzyl sulfonate (DBS), sodium dodecyl sulfate (SDS), and of a domestic detergent (Y) on the AChE activity of the crustacean cladoceran Daphnia magna. All the chemicals significantly inhibit the activity of the enzyme, both in vitro and in vivo conditions. In vitro lowest observed effect concentration (LOEC) values ra...

Recombinant Escherichia coli systems expressing organophosphorous hydrolase (OPH) have been proposed for biotransformation of toxic organophosphate compounds. However, whole cell biocatalyst systems are critically disadvantaged due to substrate diffusion limitations. To enhance whole cell biocatalytic efficiency, we engineered E. coli, for the first time, to secrete metal ion cofactor-requiring...

The present investigation deals with histopathological and histochemical studies of profenophos on liver and kidney of male albino rats and the protective effects of vitamin C and ginseng to reduce the deleterious effect induced by profenophos. Oral administration of profenophos at dose level of 1 /10 LD50 for 15 successive days induced histological changes in liver and kidney. No histological ...

Objective: A retrospective study was conducted in a tertiary care hospital collaborated with medical college, to analyze the drug therapy including antidotes administered and pattern of Organophosphorous compounds poisoning. Material methods: The data are analytically drawn from record sheets poisoning patients. collected tabulated were statistically analyzed SPSS version for Results: demograph...

A 19 year young male who consumed organophosphorous compound and required assisted mechanical ventilation for two weeks, later on developed delayed neuropathy is described.

pesticides are one of the most pollutants in aquatic ecosystems. monitoring of aquatic pollution with these compounds is very important. therefore, health status of aquatic animals can be used as a bio-indicator for pollution monitoring in surface waters. diazinon is an organophosphorous pesticide, which is found in the aquatic environment of iran. the concern has arisen over the ability of thi...