نتایج جستجو برای: organoplatinum
تعداد نتایج: 68 فیلتر نتایج به سال:
A panel of luminescent platinum(II) complexes containing bidentate N-heterocyclic carbene ligands selectively localize to the endoplasmic reticulum (ER) domain, induce ER stress and cell apoptosis. Some of them show potent photo-toxicity to cancer cells.
Carbon nanotubes have unique properties like high stability, high surface to mass ratio and so on which make them suitable for medicinal purpose applications. Treatment of cancer by organoplatinum agents like Cisplatin has become unresponsive in most cases due to low distribution of drug in biological fluids, inability of drug to cross cellular membranes and low stability in biological environm...
Carbon nanotubes have unique properties like high stability, high surface to mass ratio and so on which make them suitable for medicinal purpose applications. Treatment of cancer by organoplatinum agents like Cisplatin has become unresponsive in most cases due to low distribution of drug in biological fluids, inability of drug to cross cellular membranes and low stability in biological environm...
PURPOSE Development of novel agents and drug combinations are urgently needed for treatment of pancreatic cancer. Oxaliplatin belongs to an important class of DNA-damaging organoplatinum agents, useful in pancreatic cancer therapy. However, increased ability of cancer cells to recognize and repair DNA damage enables resistance to these agents. Poly (ADP ribose) polymerase-1 is a sensor of DNA d...
New organoplatinum(II) complexes with the general formula of Pt(N,N-L)R(2), where L is a bis(7-azaindol-1-yl) chelate ligand, R is a methyl or a phenyl, have been synthesized and investigated with the aim to understand the impact of the linker group in the L ligand on the structure and the stability of the Pt(II) complexes. The L ligands used in our investigation belong to two classes: class I ...
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