نتایج جستجو برای: osthole
تعداد نتایج: 222 فیلتر نتایج به سال:
Borneol is a natural permeation enhancer that is effective in drugs used in traditional clinical practices as well as in modern scientific research. However, its molecular mechanism is not fully understood. In this study, a mixed coarse-grained model of stratum corneum (SC) lipid bilayer comprised of Ceramide-N-sphingosine (CER NS) 24:0, cholesterol (CHOL) and free fatty acids (FFA) 24:0 (2:2:1...
prangos ferulacea is a plant found in the mediterranean and middle-east regions used as carminative, anti-flatulent, emollient and antibacterial herb. it is believed that the coumarins are responsible for some of known effects of prangos . in this research the relaxant effects of p. ferulacea coumrin rich extract as well as osthole as its main prenylated coumarins were investigated on rat ileu...
From osthole [7-methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one] (I), obtained by selective extraction of Peucedanum ostruthium (L.) W. Koch roots, ostholic acid (II) was synthetized as a result of its oxidation with chromium trioxide. From ostholic acid, through its chloride, four amides were obtained: the morpholide 1, the p-chloro-benzylamide 2, the piperidine 3 and the N-methyl-piperazide 4. ...
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