Otitis media and mastoiditis occurring in infancy have long been recognized as most troublesome disorders and, of recent years, would appear to be receiving the attention they merit. The frequency of otitis media or otitis media and mastoiditis found both in the infants' wards and in the autopsy room of the Alder Hey Children's Hospital has led to this statistical and clinical enquiry into this...

BACKGROUND Recurrent otitis media is a common problem in young children. Echinacea and osteopathic manipulative treatment have been proposed as preventive measures, but have been inadequately studied. This study was designed to assess the efficacy of Echinacea purpurea and/or osteopathic manipulative treatment (OMT) for prevention of acute otitis media in otitis-prone children. METHODS A rand...

BACKGROUND & OBJECTIVES Microbial infections in the normally sterile environment of the middle ear cavity in patients with otitis media trigger expression of Toll-like receptors (TLRs), cytokines, and nitric oxide. We evaluated the expression levels of TLR-1, -2, -4, -5, -6, and -9, interleukin (IL)-6, -8, -10, and -12, interferon-γ (IFN-γ), tumour necrosis factor-α (TNF-α), and nitric oxide (N...

Objective The objective is to perform a comprehensive review of the literature up to 2015 on the genetics and precision medicine relevant to otitis media. Data Sources PubMed database of the National Library of Medicine. Review Methods Two subpanels were formed comprising experts in the genetics and precision medicine of otitis media. Each of the panels reviewed the literature in their respecti...

BACKGROUND Previously rare A2ML1 variants were identified to confer otitis media susceptibility in an indigenous Filipino community and in otitis-prone US children. The goal of this study is to describe differences in the middle ear microbiome between carriers and non-carriers of an A2ML1 duplication variant that increases risk for chronic otitis media among indigenous Filipinos with poor healt...

This report presents the results of the clinical observation of 96 children under ten years of age with acute otitis media (107 ears) who visited our out-patient clinic from May 1986 to August 1987. The patients were classified into the following three groups according to clinical course: Group 1: 25 cases (26.0%) in which acute inflammatory findings rapidly disappeared and otitis media was cur...

'Trcatmcnt of' acut o)titis media: a controlled studv of 142 childrcn. (an .lled.Assoc7 197(;102:263-. 5 Halstcd C. Ilcpow MI. Balassaniati N, Eimmerich J, \\olinskv E. Otitis mcdia: clinical observations, microbiology, and evaluation of therapy. .lmIDisChild 1968;115:542-51. 6 Howie VM, I'loussard JH. Efficacy ot' fixed combinationi antibiotics versus separate conmponents in otitis media. Clin...

Chronic suppurative otitis media, infection of the middle ear, is a common disease in the developing countries and the complications associated with it still pose a major problem in the developing countries. The proximity of the middle ear cleft and mastoid air cells to the extracranial and intracranial compartments places structures located in these areas at increased risk of infectious compli...

Cerebral venous thrombosis as a manifestation of paraneoplastic angitis and otitis media, revealing non-Hodgkin B-cell lymphoma (NHBL), is extremely rare. A 57-year-old woman presented with headache, auditory disturbance and recalcitrant otitis media. Magnetic resonance imaging showed brain edema in the temporal lobe and transverse sinus thrombosis. External drainage under antibiotic treatment ...

Serios otitis media is one of those ear Trou­bles that has enjoyed a very extensive research two decaides.  I ts recognition in medical literature goes b,ick tc eighteenth century. Since then there has been rather little progress in this field. The dis­covery of antibiotcs and thence lessening of in­ fecticus ear diseases, attention has been paid to preserve the function of ear, and naturally...