background: based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (fsh) and luteinizing hormone (lh) put on their main effects on the granulosa and theca cells. lh is essential for androgens production. androgens are used for estradiol production by granulosa cells. profound suppression of lh concentrations in some normogonadotropic patients can cau...

Background This research investigated the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-II (AT-II) to ovarian stimulation during 24 hours in patients with polycystic ovary syndrome (PCOS). MaterialsAndMethods In this clinical trial study, 52 patients with PCOS and 8 control cases were stimulated with human chorionic gonadotropin (HCG) on the 4th ...

BACKGROUND The initial dose of recombinant Follicle Stimulating Hormone [rFSH] to be used in assisted reproduction treatment depends on several factors, mainly the cause of the infertility and the patient's age. For young patients [≤35 years] usually an initial dose of around 150 IU of rFSH is recommended, but there are no studies proving that this should actually be the standard initial dose. ...

Purpose To compare the efficacy of two regimens of low dose human chorionic gonadotropin (hCG) on follicular response and oocyte maturation in women with polycystic ovarian syndrome (PCOS). Methods Ninety women with PCOS who underwent assisted reproduction were eligible for this controlled, prospective, randomized study. Our trial was performed at Royan Institute Reproductive Research Center ov...

Initial attempts at obtaining a pregnancy by in vitro fertilization and embryo transfer (IVF-ET) were conducted in a natural cycle (Edwards et al., 1980). It soon became clear that ovarian stimulation using gonadotropins provided a useful tool to obtain more oocytes and increase the chance for success. This resulted in the need to monitor ovarian stimulation, based on serial sonographic assessm...

BACKGROUND In women, anti-Müllerian hormone (AMH) levels may represent the ovarian follicular pool and could be a useful marker of ovarian reserve. The clinical application of AMH measurement has been proposed in the prediction of quantitative and qualitative aspects in assisted reproductive technologies (ART). In men AMH is secreted in both the serum and seminal fluid. Its measurement may be u...

Polycystic Ovarian Syndrome (PCOS) is a hyper androgenic condition in female with persistent oligo-anovulation. Between the age of 18 and 44, almost 5% to 10% females are impacted by this condition. The most prevalent issue world infertility, which inability conceive after continuous one-year period exposure regular, unprotected, typical coitus. Three-quarters forty percent all human infertilit...

ovarian hyperstimulation syndrome (ohss) is a unique iatrogenic complication of controlled ovarian stimulation (coh)/in vitro fertilization (ivf) in reproductive endocrinology occurring during the luteal phase or early pregnancy. it can have a serious impact on the patient�s health. with the expansion of the assisted reproductive techniques (art) from 1978, the incidence of ohss is increasing w...