the article analyzes literature problems using as a parameter the quaternary prevention concept, introducing guidelines to have good shared decisions that avoid overdiagnosis and overtreatment and improve the quality of life. the author proposes a four-step approach: reliable evidence, awareness about populations profile, independent research analysis, and an understandable format by ordinary p...

screening for lung cancer in asbestos occupational exposure: a systematic review and meta-analysis. Chest 2014;145:1339-1346. 14. Tammemägi MC, Katki HA, Hocking WG, Church TR, Caporaso N, Kvale PA, Chaturvedi AK, Silvestri GA, Riley TL, Commins J, et al. Selection criteria for lung-cancer screening. N Engl J Med 2013;368: 728–736. 15. Field JK, Oudkerk M, Pedersen JH, Duffy SW. Prospects for p...

Overdiagnosis is a harmful consequence of screening which particularly challenging to estimate. An unbiased setting measure overdiagnosis in breast cancer requires comparative data from screened and an unscreened cohort for at least 30 years. Such randomised will not become available, leaving us with observational over shorter time periods outcomes modelling. This collaborative effort the Inter...

Distinguishing the sick from the healthy has always been a fundamental challenge for medicine. A chief concern has been to guard against missing disease, with the focus on problems of underdiagnosis and undertreatment. Yet with the modern technological expansion of healthcare in rich developed nations, sceptical voices have long warned of the flipside—too much medicine. Mounting evidence about ...

Overdiagnosis is a phenomenon in which screening identities cancer which may not go on to cause symptoms or death. Women over 65 who develop breast cancer bear the heaviest burden of overdiagnosis. This work introduces novel machine learning algorithms to improve diagnostic accuracy of breast cancer in aging populations. At the same time, we aim at minimizing unnecessary invasive procedures (th...