Recent publications have raised concerns about the reliability of microarray technology because of the lack of reproducibility of differentially expressed genes (DEGs) from highly similar studies across laboratories and platforms. The rat toxicogenomics study of the MicroArray Quality Control (MAQC) project empirically revealed that the DEGs selected using a fold change (FC)-based criterion wer...

Niche dependent differential gene loss and overlapping genes have been proposed as means of achieving genome reduction by retaining indispensable genes and compressing maximum amount of information in available sequence space. Herein, we analyzed the differential gene loss and overlapping genes in bacterial genomes with different lifestyles. Our results clearly suggest that gene loss and overla...

Migraine and epilepsy are distinct neurological diseases with specific clinical features underlying pathophysiological mechanisms. However, numerous studies have highlighted the complex multifaceted relationships between two conditions. The headache manifest themselves in different ways. Firstly, diagnosis of these disorders may be challenging view possible overlapping. While post-ictal is a fr...

OBJECTIVE Fatigue and depression are highly comorbid phenotypes with partially overlapping symptoms. The main aims of the present study are to: (i) identify the risk of current fatigue and depression; (ii) determine if the depression symptoms experienced by individuals who are fatigued (N=766) and non-fatigued (N=1849) are different; and (iii) identify if the fatigue symptoms experienced by dep...

Introduction Psychosis and dissociative disorders are both described in the DSM-5 as different diagnostic categories. However, a high comorbidity of these diagnoses has been observed studies, perhaps due to overlapping symptoms between them. Objectives A systematic review about psychotic spectrum Methods Presentation case patient existing literature on differential diagnosis disorder other diso...

Multiple Sclerosis (MS), Myalgic Encephalomyelitis (ME), and Chronic Fatigue syndrome are debilitating chronic illnesses, with some overlapping symptoms. However, few studies have compared and contrasted symptom and disability profiles for these illnesses for the purpose of further differentiating them. The current study was an online self-report survey that compared symptoms from a sample of i...