INTRODUCTION  IgA nephropathy (IgAN) is characterized by a highly heterogeneous clinical course, which results in controversies regarding the assessment of individual prognosis and establishing the optimal treatment approach. OBJECTIVES  The aim of the present study was to define risk factors for IgAN progression. We evaluated histopathological features derived from the Oxford classification ...

C om m en ta ry Implication for health policy/practice/research/medical education: Oxford classification system was based on actual clinical data, international collaboration, and validation of the reproducibility of defining pathologic lesions. The strongest pathologic predictor of clinical outcome in IgA nephropathy is the extent of tubular atrophy and interstitial fibrosis. A R T I C L E I N...

BACKGROUND IgA nephropathy is defined by the presence of IgA-dominant glomerular deposits. Within this definition, there is variation in the location of IgA and the presence of other immunoglobulins. The Oxford classification of IgA nephropathy identifies four histological features that are independent predictors of clinical outcome but does not include immunostains. Here, we investigate the po...

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Classification of brain tissues is becoming an increasingly useful tool for investigating the aging brain or disease-induced brain alterations. Numerous strategies have been proposed to classify brain tissues into white matter (WM), gray matter (GM) and cerebrospinal fluid (CSF). However, many of them fail when classifying specific regions with low contrast between tissues (e.g. cerebellum gray...

We have developed a deep learning network for classification of different flowers. For this, we have used Visual Geometry Group’s 102 category flower data-set having 8189 images of 102 categories from Oxford University. The method is basically divided in two parts i.e. Image segmentation and classification. We have compared two different Convolutional Neural Network architectures GoogLeNet and ...

We analysed data from the Oxford hip and knee questionnaires collected by the New Zealand Joint Registry at six months and five years after joint replacement, to determine if there was any relationship between the scores and the risk of early revision. Logistic regression of the six-month scores indicated that for every one-unit decrease in the Oxford score, the risk of revision within two year...

Objective. Studies of previous cohorts have demonstrated an association between a status of overweight/ obesity and the presence of knee and hand osteoarthritis (OA). However, no data on the effect of these factors on the OA burden are available. The aim of the present study was to analyze the effect of being overweight or obese on the incidence of routinely diagnosed knee, hip, and hand OA. Me...