The aim of the study was to evaluate the antioxidant and free radical scavenging properties and to determine the phenolic content of the ethanol extract from five Mentha species [M. longifolia (L.) Huds., M. piperita L., M. pulegium L., M. rotundifolia (L.) Huds., and M. spicata L.]. The antioxidant activities of the extracts were investigated with two different methods, 2,2’-diphenyl-1-picrylh...

objective: previous studies showed that grape seed extract (gse) is an excellent natural substance with potent antioxidant effect and free radical scavenger. this study aimed to evaluate the effect of gse on motor dysfunctions and thalamic local electroencephalography (eeg) frequency bands' powers in rats with parkinson's disease (pd). materials and methods: in this study 8 µg 6-hydro...

Hepatic microsomes prepared from rats pretreated with hematoporphyrin derivative (HPD) undergo rapid enhancement of lipid peroxidation in the presence of solar radiation (approximately 400 nm). Quenchers of singlet oxygen, including 2,5-dimethylfuran, histidine, and beta-carotene, and inhibitors of the hydroxyl radical, including benzoate, mannitol, and ethanol, largely protected against the en...

Glucose is one of the most important sources of cellular nutrition and glucose deprivation induces various cellular responses. In Schizosaccharomyces pombe, zinc finger protein Rst2 is activated upon glucose deprivation, and regulates gene expression via the STREP (stress response element of Schizosaccharomyces pombe) motif. However, the activation mechanism of Rst2 is not fully understood. We ...

Direct bypass procedures effectively improve cerebral hemodynamics immediately after surgery in patients with moyamoya disease (MMD). However, they carry the risk of postoperative hyperperfusion that could lead to neurological deficits. We reported previously that hyperperfusion-related transient neurological deficits (TNDs) occurred in 31.5% of adult patients who underwent direct bypass proced...

3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone), an effective free radical scavenger, provides neuroprotection in stroke models and patients. In this study, we investigated its neuroprotective effects in a chronic rotenone rat model for Parkinson's disease. Here we showed that a five-week treatment with edaravone abolished rotenone's activity to induce catalepsy, damage mitochondria and degener...

Panchenko, Maria V., Harrison W. Farber, and Joseph H. Korn. Induction of heme oxygenase-1 by hypoxia and free radicals in human dermal fibroblasts. Am. J. Physiol. Cell Physiol. 278: C92–C101, 2000.—Heme oxygenase-1 (HO-1) catalyzes the rate-limiting step in heme catabolism and presumably is involved in cellular iron homeostasis. It is induced by a variety of cellular stresses, including oxyge...

the aim of the study was to evaluate the antioxidant and free radical scavenging properties and to determine the phenolic content of the ethanol extract from five mentha species [m. longifolia (l.) huds., m. piperita l., m. pulegium l., m. rotundifolia (l.) huds., and m. spicata l.]. the antioxidant activities of the extracts were investigated with two different methods, 2,2’-diphenyl-1-picrylh...

Hermatypic-zooxanthellate corals track the diel patterns of the main environmental parameters - temperature, UV and visible light - by acclimation processes that include biochemical responses. The diel course of solar radiation is followed by photosynthesis rates and thereby elicits simultaneous changes in tissue oxygen tension due to the shift in photosynthesis/respiration balance. The recurre...