The endothelium plays an active role in ischemia/reperfusion injuries. Herein, we report the effect of a single or successive cycles of anoxia/reoxygenation (A/R) on the mitochondrial respiratory function of equine endothelial cells (cultured from carotids) monitored by high resolution oxymetry, and on their production of reactive oxygen species (ROS). ROS were measured by electron paramagnetic...

CONTEXT The subjectivity of pain causes enormous difficulties in evaluating neonatal pain with a single, practical and easy-to-apply tool. Pain evaluation in the neonatal period should be performed by valid, safe, useful and feasible methods. OBJECTIVE To evaluate the validity of the Neonatal Facial Coding System (NFCS), Neonatal Infant Pain Scale (NIPS), heart rate (HR) and O2 saturation (O2...

BACKGROUND This study aimed to evaluate the renal tubular function in the patients with congenital heart disease using β2-microglobulin. METHODS In this case-control study, based on oxymetry, the patients with congenital heart disease were divided into two groups of cyanotic (n=20) and acyanotic (n=20). Congenital heart disease was diagnosed by echocardiography. Healthy individuals within the...

The aim of this study was to investigate both the efficacy and safety of sedation with propofol during urgent therapeutic gastroscopy in patients with upper gastrointestinal bleeding. This prospective study included a total of 110 patients. Propofol was administered intravenously at the starting dose of 1 mg/kg body weight and was followed by repeated doses. Oxygen saturation and heart rate wer...

The patient is a 41-year-old woman who was referred to our hospital because of an abnormal chest radiograph. On admission, she was asymptomatic, but her cardiac silhouette was shifted to the right on chest radiograph. From contrast-enhanced chest computed tomography (CT), we suspected that the right upper pulmonary vein connected to the inferior vena cava. The CT also revealed hypoplasia of the...

BACKGROUND Arterial oxygen saturation (SaO2) diminishes with altitude. AIM To know the values of SaO2 in healthy mountaineers during the ascent of a mountain higher than 8,000 metres. METHOD On occasion of an expedition to Gasher brum II (8,035 m), SaO2 at rest was measured by pulse oxymetry during the approach march, in the base camp (on day one and one month later), in camps II and III, d...

The concentration of carboxyhaemoglobin (COHb) is often estimated from measurements of carbon monoxide in the exhaled air (COexh). This study investigates whether the presence of airflow obstruction significantly alters the relationship between COexh and COHb. Eighty-one regular smokers were prospectively studied and divided in four groups according to the presence and severity of airflow obstr...

Continuous wave Near InfraRed Spectroscopy (NIRS) has been used successfully in clinical environments for several years to detect cerebral activation thanks to oxymetry (i.e. absorption of photons by oxyand deoxyhemoglobin) measurement. The goal of our group is to build a clinically-adapted time-resolved NIRS setup i.e. a setup that is compact and robust enough to allow bedside measurements and...

Authors investigated sedation quality in children for auditory brainstem response testing. Two-hundred and seventy-six sedation procedures were retrospectively analyzed using recorded data focusing on efficacy of sedation and complications. Intramuscular ketamine-midazolam-atropine combination was administered on sedation preceded by narcotic suppository as pre-medication. On using the combinat...

BACKGROUND AND OBJECTIVE Idiopathic pulmonary fibrosis (IPF) patients report fatigue, possibly reflecting sleep disturbance, but little is known about sleep-related changes. We compared ventilation and gas exchange during sleep and exercise in a cohort of IPF patients, and evaluated associations with selected biological markers. METHODS Twenty stable IPF patients (aged 67.9 ± 12.3 [SD]) under...