Background: A significant bone defect is a condition wherein the cannot repair spontaneously. Therefore, replacing defects with substitution remains reconstructive concern for orthopaedic surgeons. Bone Graft Substitution (BGS) are classified broadly, such as grafts (autograft, allograft, and xenograft) synthetic ceramics (hydroxyapatite, calcium sulphate). This study aims to determine e...

Age at menarche (AAM) is a complex trait involving both genetic and environmental factors. To identify the genetic factors associated with AAM, we conducted a large-scale meta-analysis of genome-wide association studies using more than 15,000 Japanese female samples. Here, we identified an association between SNP (single nucleotide polymorphism) rs364663 at the LIN28B locus and AAM, with a P-va...

Introduction: A bone graft is a substitute material that has been widely used in grafting. In general, can be resorbable and replace normal the healing process within few months, because principle nature of osteoconduction, osteoinduction, osteogenic. One synthetic materials commonly hydroxyapatite (HA), which identical to crystal structure from bone. Review: Hydroxyapatite graft, most now due ...

The effect of electron beam irradiation of stoichiometric hydroxyapatite (Ca10(PO4)6(OH)2, HAP) is investigated using electron energy loss spectroscopy (EELS) in the scanning transmission electron microscope (STEM) mode equipped with a LaB6 gun. Initial irradiation at 160 A cm −2 dose rate shows no modification of the low loss spectra. No difference of mass loss for Ca, O and P is observed for ...

Synthesis of nanosized particle of Ag-doped hydroxyapatite with antibacterial properties is in the great interest in the development of new biomedical applications. In this article, we propose a method for synthesized the Ag-doped nanocrystalline hydroxyapatite. A silver-doped nanocrystalline hydroxyapatite was synthesized at 100°C in deionized water. Other phase or impurities were not observed...